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Table 2 Adjuvant interventions - added to clozapine

From: Treatment resistant schizophrenia: a comprehensive survey of randomised controlled trials

Name of intervention

Number

Cochrane review

Studies

Participants

Antipsychotics

 

  Amisulpride

4

322

[21]

  Aripiprazole

5

349

 

  Fluphenazine

1

60

 

  Haloperidol

2

116

 

  Paliperidone

1

70

 

  Pipotiazine

1

84

 

  Quetiapine

2

136

[21]

  Risperidone

10

646

[21]

  Sertindole

1

50

 

  Sulpride

2

150

[21,22]

  Ziprasidone

3

150

[21]

  Clozapine added to 'other antipsychotics'

2

100

 

Antidepressants

 

  Duloxetine

1

33

 

  Fluvoxamine

1

68

 

Anticonvulsants/mood stabilisers

 

  Valproate

1

34

[23]*

  Lamotrigine

2

85

[24]*

  Lithium

3

152

[25]*

Antimicrobials

 

  Inosine

1

66

 

Herbal

 

  Ginkgo Biloba

1

42

 

Anti-diabetic

 

Metformin

1

61

 

Selective norepinephrine reuptake inhibitor

 

  Atomoxetine

1

126

 

Drugs Used in Dementia

 

  Mematine

1

21

[26]**

Amino acids

 

  Glycine

2

31

[27]*

  1. *Review includes interventions that weren't just added to clozapine.
  2. **Protocol and intervention wasn't specifically added to clozapine.
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BMC Psychiatry

ISSN: 1471-244X

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