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Table 3 Adjuvant interventions - added to antipsychotics other than clozapine

From: Treatment resistant schizophrenia: a comprehensive survey of randomised controlled trials

Name of intervention

Number

Cochrane review

Studies

Participants

Added to specific antipsychotic

Olanzapine

 

  Antipsychotic

Chlorpromazine

1

39

 
 

Sulpride

2

114

 

Risperidone

 

  Antipsychotic

Quetiapine

1

144

 

Chlorpromazine

 

  Movement disorder drugs

LDOPA

1

8

 

Haloperidol

    

  Serotonin 5-HT3 receptor antagonist

Ondansetron

1

121

 

Added to unspecified antipsychotic

    

  Amino Acids

Glycine

3

50

[27]

 

Serine

1

39

[27]

  Antidepressants

Citalopram

1

18

 
 

Escitalopram

1

30

 
 

Mianserin

1

18

 
 

Sertraline

1

77

 

  Anticonvulsants and mood stabilisers

Valproate

2

140

[23]

 

Carbamazepine

3

79

[28]

 

Topiramate

2

86

 
 

Lamotrigine

1

38

[24]

 

Lithium

5

227

[25]

  Antimicrobials

D-Cycloserine

2

35

[27]

 

Ketoconazole

2

24

 

  Herbal

Ning Xin Tang

1

60

 
 

Ginkgo Biloba

1

82

 
 

Yi Gan San

1

59

 

  Movement disorder drugs

Apomorphine

1

18

 
 

Tetrabenazine

1

41

 

  Opioid acting drugs

Methadone

1

7

 

  Salt or ester of benzoic acid

Benzoate

1

60

 

  Histamine H2 receptor antagonist

Famotidine

1

30

 

  Oestrogen receptor antagonist

Tamoxifem

1

26

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