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Table 2 Association between major depressive disorder and Parkinson's disease and other clinical correlates

From: Major depressive disorder in Parkinson’s disease: a cross-sectional study from Sri Lanka

Variables

Total no (%)

Depression

OR (95% CI)

pvalue

  

Yes

No

  

Age of PD onset (years)

     

<40

10(9.6%)

4(40.0%)

6(60.0%)

1

0.813

41-50

20(19.2%)

9(45.0%)

11(55.0%)

1.22(0.26-5.73)

 

51-60

42(40.4%)

13(31.0%)

29(69.0%)

0.67(0.16-2.79)

 

61-70

26(25.0%)

11(42.3%)

15(57.7%)

1.10(0.24-4.85)

 

>70

6(5.8%)

2(33.3%)

4(66.7%)

0.75(0.09-6.23)

 

Duration of PD (years)

     

< 5

42(40.4%)

28(66.7%)

14(33.3%)

1

0.114

5 to 10

28(26.9%)

13(46.4%)

15(53.6%)

2.30(0.86-6.15)

 

> 10

34(32.7%)

24(70.6%)

10(29.4%)

0.83(0.31-2.21)

 

Levodopa dose (mg/day)

     

< 250

15(14.4%)

4(26.7%)

11(73.3%)

1

0.8

250 - 500

41(39.4%)

16(39.0%)

25(61.0%)

1.76(0.47-6.49)

 

500 - 750

22(21.2%)

10(45.5%)

12(54.5%)

2.29(0.55-9.47)

 

750 - 1000

15(14.4%)

5(33.3%)

10(66.7%)

1.37(0.28-6.60)

 

1000 - 1250

9(8.7%)

4(44.4%)

5(55.6%)

2.20(0.38-12.57)

 

Ropinirole treatment

     

Yes

21(20.2%)

11(52.4%)

10(47.6%)

10(47.6%)

0.115

No

83(79.8%)

28(33.7%)

55(66.3%)

55(66.3%)

 

Diabetes

     

Yes

12(11.5%)

9(75.0%)

3(25.0%)

6.2(1.56-24.5)

0.004

No

92(88.5%)

30(32.6%)

62(67.4%)

1

 

Significant chronic medical illness comorbid with PD

     

Yes

48(46.2%)

22(45.8%)

26(54.2%)

1.96

0.086

No

56(53.8%)

17(30.4%)

39(69.6%)

1

 

Hoehn-Yahr stage

     

I and II

24(23.1%)

2(8.3%)

22(91.7%)

1

0.003

III

55(52.9%)

27(49.1%)

28(50.9%)

10.61(2.27-49.53)

 

IV and V

25(24.0%)

10(40.0%)

15(60.0%)

7.33(1.40-38.33)

 

Schwab-England score (%)

     

–80

43(41.4%)

8(18.6%)

35(81.4%)

1

0.008

50-70

45(43.3%)

24(53.3%)

21(46.7%)

5.00(1.90-13.13)

 

30-40

12(11.5%)

5(41.7%)

7(58.3%)

3.12(0.78-12.43)

 

–20

4(3.8%)

2(50.0%)

2(50.0%)

4.37(0.53-35.90)

 

Caregiver

     

Independent

25(24.0%)

5(20.0%)

20(80.0%)

1

0.038

Dependent

79(76.0%)

34(43.0%)

45(57.0%)

3.02(1.03-8.86)

 
  1. OR – Odds ratio.