From: Predominant polarity in bipolar disorder and validation of the polarity index in a German sample
 | DPP (N = 169) | MPP (N = 46) | Chi Square | p adj 2 |
---|---|---|---|---|
N (50.3%) | N (13.7%) | |||
Sex | Â | Â | 5.49 | .019 |
 Female | 116 (68.6) | 23 (50) | ||
 Male | 53 (31.4) | 23 (50) | ||
Subtype | Â | Â | 31.45 | <.000* |
 Bipolar I | 80 (47.3) | 43 (93.5) |  |  |
 Bipolar II | 89 (52.7) | 3 (6.5) |  |  |
Family history of psychiatric disorders | 138 (81.7) | 35 (76.1) | 0.71 | .398 |
Family history of suicide | 59 (34.9) | 12 (26.1) | 1.27 | .259 |
Rapid cycling | 19 (11.2) | 3 (6.5) | 0.88 | .349 |
Psychotic symptoms | 22 (13.0) | 13 (28.3) | 6.16 | .013 |
First Episode Mania | 11 (6.5) | 30 (65.2) | 80.75 | <.000* |
Mania with irritable mood | 52 (30.8) | 34 (73.9) | 28.04 | <.000* |
Mixed Episodes | 55 (34.6) | 16 (39.0) | 0.28 | .597 |
Suicide attempts (life time) | 68 (40.2) | 15 (32.6) | 0.89 | .346 |
Substance abuse (life time) | 18 (10.7) | 10 (21.7) | 3.93 | .481 |
Treatment | Â | Â | Â | Â |
Lithium | 74 (43.8) | 30 (65.2) | 6.65 | .010 |
Other Mood Stabilizers1 | 63 (37.3) | 26 (56.5) | 5.52 | .019 |
Antipsychotics (incl. quetiapine) | 117 (69.2) | 43 (93.5) | 11.17 | .001* |
Antidepressants | 121 (71.6) | 14 (30.4) | 26.22 | <.000* |
 | Mean (SD) | Mean (SD) | t | p adj. 2 |
Age | 50.3 (14.8) | 52.1 (12.2) | -.765 | .451 |
Age of Onset | 29.8 (11.8) | 28.5 (10.4) | .667 | .505 |
Age of first depression | 29.7 (12.1) | 31.6 (12.1) | -0.85 | .396 |
Age of first mania | 37.1 (14.5) | 28.8 (11.0) | 3.43 | .001* |
Duration of illness | 20.5 (12.5) | 23.6 (12.6) | -1.45 | .148 |
Total number of episodes | 11.1 (10.2) | 10.7 (6.3) | 0.282 | .778 |
Number of manic episodes | 2.3 (2.5) | 8.3 (5.5) | -10.56 | <.000* |
Number of depressive episodes | 8.6 (8.0) | 2.4 (2.0) | 5.26 | <.000* |
Number of mixed episodes | 1.0 (2.8) | 0.71 (1.2) | .736 | .463 |