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Table 1 Description of the sample

From: Patterns of initiation of second generation antipsychotics for bipolar disorder: a month-by-month analysis of provider behavior

  Bipolar population (N =170,713) a Never initiated SGA during study period (N =81,167, 64.1% of those eligible for SGA initiation) Ever initiated SGA during study period (N =45,389, 35.9% of those eligible for SGA initiation)
Variable Mean SD Mean SD Mean SD
Age at study entry b 50.3 13.3 51.6 13.6 48.3 13.0
  N % N % N %
Gender (female) 24,076 14.1 10,804 13.3 6,954 15.3
Disability status ≥50% c,d 52,584 30.9 23,067 28.5 13,148 29.0
Marital status d 76,315 44.9 34,786 43.3 18,265 40.5
Race/ethnicity e       
White 127,742 82.2 60,381 83.0 34,425 82.6
African American 20,884 13.4 9,305 12.8 5,588 13.4
Hispanic 4,034 2.6 1,861 2.6 891 2.1
Other race/ethnicityc 2,684 1.7 700 1.0 455 1.1
Clinical/treatment course d       
Psychotic features 22,119 13.0 6,822 8.4 7,322 16.1
Bipolar type I (versus type II/NOS)f 145,128 85.0 68,344 84.2 40,283 88.8
Antidepressant prescription 139,807 81.9 55,920 68.9 34,969 77.0
Antimanic prescription 128,596 75.3 51,820 63.8 35,755 78.8
Any psychiatric hospitalization 64,117 37.6 23,284 28.7 21,330 47.0
Comorbidities d       
Diabetes 42,517 24.9 20,679 25.5 10,138 22.3
Obesity 61,182 35.8 27,469 33.8 16,581 36.5
Hyperlipidemia 101,886 59.7 47,770 58.9 26,190 57.7
Substance abuse 79,658 46.7 33,202 40.9 23,280 51.3
Tobacco use disorder 86,311 50.6 37,406 46.1 24,182 53.3
Anxiety disorder 102,130 59.8 43,310 53.4 27,331 60.2
Sleep disorder 29,355 17.2 11,762 14.5 8,072 17.8
Cardiac dysrhythmia 19,600 11.5 9,509 11.7 4,827 10.6
Liver disorder 22,332 13.1 9,460 11.7 5,997 13.2
Kidney disorder 19,044 11.2 9,271 11.4 4,729 10.4
Thyroid disorderc 20,226 11.9 9,429 11.6 5,566 12.3
Traumatic brain injury 9,209 5.4 3,629 4.5 2,557 5.6
  1. aIncludes data on those patients ineligible to be labeled as SGA initiator or SGA non-initiator (N = 44,157).
  2. bUnless otherwise stated, all comparisons between the ever-initiated and never-initiated groups were p < .0001.
  3. cFor these variables, comparison between the ever-initiated and never-initiated groups was p > .0001 (>50% disability status: p = .0385; other race/ethnicity: p = .0120; thyroid disorder, p = .0006).
  4. dUnless otherwise stated, these variables were coded as present if they occurred at any point during the study period.
  5. eBased on smaller N, due to missing values for 9% of the sample.
  6. fAt patient’s last available data during the study period.