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Table 2 Index antipsychotic therapies

From: Antipsychotic patterns of use in patients with schizophrenia: polypharmacy versus monotherapy

Therapy Total N = 4,156 n (%)
Patients on monotherapy (% of total) 3,188 (76.7)
Number of patients by type of antipsychotic monotherapy (% of monotherapy)  
  Risperidone 765 (24.0)
  Aripiprazole 536 (16.8)
  Olanzapine 505 (15.8)
  Quetiapine 437 (13.7)
  Ziprasidone 261 (8.2)
  Clozapine 200 (6.3)
  Other second-generation antipsychotic 57 (1.8)
  First-generation antipsychotic 427 (13.4)
Total on polypharmacy (% of total) 968 (23.3)
Number of patients by type of antipsychotic polypharmacy combinations (% of polypharmacy)  
  Combinations with first-generation antipsychotics 257 (26.5)
  Combinations with olanzapine 216 (22.3)
  Combinations with risperidone 210 (21.7)
  Combinations with other second-generation antipsychotics 186 (19.2)
  Combinations with clozapine 99 (10.2)
Top 5 polypharmacy combinations  
  Quetiapine and risperidone 96 (9.9)
  Quetiapine and aripiprazole 94 (9.7)
  Quetiapine and first-generation antipsychotic 83 (8.6)
  Aripiprazole and risperidone 65 (6.7)
  Aripiprazole and olanzapine 65 (6.7)