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Table 2 Index antipsychotic therapies

From: Antipsychotic patterns of use in patients with schizophrenia: polypharmacy versus monotherapy

Therapy

Total N = 4,156 n (%)

Patients on monotherapy (% of total)

3,188 (76.7)

Number of patients by type of antipsychotic monotherapy (% of monotherapy)

 

  Risperidone

765 (24.0)

  Aripiprazole

536 (16.8)

  Olanzapine

505 (15.8)

  Quetiapine

437 (13.7)

  Ziprasidone

261 (8.2)

  Clozapine

200 (6.3)

  Other second-generation antipsychotic

57 (1.8)

  First-generation antipsychotic

427 (13.4)

Total on polypharmacy (% of total)

968 (23.3)

Number of patients by type of antipsychotic polypharmacy combinations (% of polypharmacy)

 

  Combinations with first-generation antipsychotics

257 (26.5)

  Combinations with olanzapine

216 (22.3)

  Combinations with risperidone

210 (21.7)

  Combinations with other second-generation antipsychotics

186 (19.2)

  Combinations with clozapine

99 (10.2)

Top 5 polypharmacy combinations

 

  Quetiapine and risperidone

96 (9.9)

  Quetiapine and aripiprazole

94 (9.7)

  Quetiapine and first-generation antipsychotic

83 (8.6)

  Aripiprazole and risperidone

65 (6.7)

  Aripiprazole and olanzapine

65 (6.7)