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Table 2 Offspring assessments

From: A familial risk enriched cohort as a platform for testing early interventions to prevent severe mental illness

Domain Method Source Age
Descriptive variables    
Demographics Questionnaire Parent 0-25
Socioeconomic status Questionnaire Parent 0-25
  FAS Offspring 7-25
Height, weight, head & waist circumference Measurement Offspring 0-18
Pubertal status Questionnaire Offspring 9-16
Diagnosis K-SADS Offspring 5-21
  SCID-5 Offspring 18-25
General psychopathology CBCL Parent 5-15
  CBCL-YSR Offspring 11-17
Personality risk factors SURPS Offspring 11-15
Mood state MFQ Offspring 7-17
Self-control, frustration tolerance TOF Rater 3-25
Substance use DUSI-R Offspring 9-25
Functional outcomes    
General functioning CIS Rater 9 - 17
General, role and social functioning GAF, GF-R, GF-S Rater 11-25
Quality of life CHQ Parent 5 - 18
  CHQ Offspring 9 - 18
  QOL Offspring 18 - 25
Activities and milestones Questionnaire Parent 0 - 17
   Offspring 9 - 25
Affective lability    
Affective lability CALS-P Parent 5-16
Affective lability CALS-C Offspring 13-16
Affective lability ALS Offspring 17-25
Self-control, frustration tolerance TOF Rater 3-25
Anxiety    5-25
Anxiety (disorders) K-SADS/SADS-P Offspring 5-16
Anxiety (dimension) CBCL Parent 11-18
Anxiety (dimension) CBCL-YSR Offspring 3-5
Anxiety (dimension) S-CAS Parent 5-17
Anxiety (dimension) S-CAS Offspring 8-17
Anxiety (dimension) SCARED Parent 8-25
Anxiety (dimension) SCARED Offspring 8-25
Psychotic symptoms    
Psychotic-like experiences Funny Feelings Offspring 7-18
Psychotic symptoms K-SADS Parent 7-18
Attenuated psychotic symptoms SIPS Offspring 12-25
Psychotic symptoms PANSS Offspring 14-25
Basic symptoms    
Basic Symptoms SPI Offspring 6-25
Sleep CSHQ Parent 4-12
  SSR Offspring 6-14
  SSHS Offspring 15-17
  PSQI Offspring 18-25
Functional somatic symptoms    
Somatic symptoms CBCL Parent 5-15
Somatic symptoms CBCL-YSR Offspring 11-17
Cognitive ability & development    
General cognitive ability WPPSI Offspring 3-5
  WASI Offspring 6-25
Attention/Processing Digit-Symbol Coding Offspring 6-25
Verbal learning and memory CVLT Offspring 6-15
  Story recall (CMS) Offspring 16-25
  Logical Memory (WMS) Offspring 8-25
Non-verbal memory BVRT Offspring 6-25
Executive function, working memory Letter-Number Sequencing Offspring 6-25
Spatial working memory CANTAB Offspring 5-25
Verbal fluency D-KEFS Offspring 7-15
  COWAT Offspring 16-25
Planning, visuospatial organization ROCF Offspring 11-25
Emotional decision making CANTAB Offspring 8-25
  1. Abbreviations: Abbreviations: FAS = Family Affluence Scale; K-SADS = Kiddie Schedule for Affective Disorders and Schizophrenia SCID-5 Structured Clinical Interview for DSM-5 Disorders; CBCL = Child Behaviour Checklist; CBCL-YSR = Child Behaviour Checklist - Youth Self Report; SURPS = Substance Use Risk Profile Scale; MFQ = Mood and Feelings Questionnaire; TOF = Test Observation Form; DUSI-R – Drug Use Screening Inventory – Revised; CIS = Columbia Impairment Scale; GF-R = Global Functioning: Role; GF-S = Global Functioning: Social; GAF = Global Assessment of Functioning; CHQ = Child Health Questionnaire; QOL = Quality of Life Short Form; CALS = Child Affective Lability Scales; ALS = Affective Lability Scales; SCAS = Spence Child Anxiety Scale; SCARED = Screen for Child Anxiety Related Disorders; SIPS = Structured Interview for Prodromal Symptoms; PANSS = Positive and negative Symptom Scale; SPI = Schizophrenia Proneness Instrument; CSHQ = Children’s Sleep Habits Questionnaire; SSR = Sleep Self Report; SSHS = School Sleep Habits Survey, PSQI = Pittsburgh Sleep Quality Index; WPPSI = Wechsler Preschool and Primary Scale of Intelligence, WASI = Wechsler Abbreviated Scale of Intelligence; CVLT = California Verbal Learning Task; WMS = Wechsler Memory Scale; BVRT = Benton Visual Retention Task; D-KEFS = Delis Kaplan Executive Functioning System Verbal Fluency Index; COWAT = Controlled Oral Ward Association Test; CANTAB = Cambridge Neuropsychological Test Automated Battery.