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Table 3 The effect of escitalopram on expression of mRNA Bax and Bcl-2 in myocardial cells in rats with depression during myocardium ischemia/reperfusion (mean ± SEM, copies/g RNA)

From: The effects of escitalopram on myocardial apoptosis and the expression of Bax and Bcl-2 during myocardial ischemia/reperfusion in a model of rats with depression

Group Bax Bcl-2 Bax/Bcl-2
D 0.274 ± 0.0294 0.109 ± 0.0101 2.68 ± 0.14
DI/R 0.443 ± 0.0282* 0.398 ± 0.0216* 1.23 ± 0.25*
Escitalopram + DI/R 0.317 ± 0.0291 0.576 ± 0.0317 0.56 ± 0.28
  1. Note: *P < .01 vs D group; P < .01vs DI/R group.
  2. D group: depression group, DI/R group: depression with myocardium ischemia/reperfusion), escitalopram + DI/R group: escitalopram + depression with myocardium ischemia/reperfusion.