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Table 4 The effect of escitalopram on expression of protein Bax and Bcl-2 in myocardial cells in rats with depression during myocardium ischemia/reperfusion (mean ± SEM, IOD)

From: The effects of escitalopram on myocardial apoptosis and the expression of Bax and Bcl-2 during myocardial ischemia/reperfusion in a model of rats with depression

Group Bax Bcl-2 Bax/ Bcl-2
D 5.37 ± 0.42 2.17 ± 0.29 2.55 ± 0.21
DI/R 9.45 ± 0.76* 4.97 ± 0.74* 2.06 ± 0.22*
Escitalopram + DI/R 6.62 ± 0.38 6.18 ± 0.56 1.05 ± 0.18
  1. Note: *P < .01 vs D group; P < .01vs DI/R group.
  2. D group: depression group, DI/R group: depression with myocardium ischemia/reperfusion), escitalopram + DI/R group: escitalopram + depression with myocardium ischemia/reperfusion.