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Table 1 Subgroup analyses of relative risk of coronary heart disease

From: Depression and the risk of coronary heart disease: a meta-analysis of prospective cohort studies

 

No of reports

Relative risk

(95% CI)

I 2

P for heterogeneity

Coronary heart disease

     

Primary analysis

27*

1.31

1.19 to 1.45

70.50%

<0.001

Subgroup analyses for coronary heart disease

Sex

     

Men

13

1.38

1.17 to 1.61

74.60%

<0.001

Women

8

1.17

1.01 to 1.36

55.50%

0.028

Combined

13

1.36

1.17 to 1.57

56.50%

0.006

Mean age at baseline, y

     

≥65

13

1.35

1.14 to 1.59

81.20%

<0.001

<65

21

1.3

1.17 to 1.44

61.40%

<0.001

Publication year

     

Before 2005

15

1.47

1.23 to 1.75

62.30%

0.001

2005-2014

19

1.24

1.13 to 1.37

74.30%

<0.001

Duration of follow-up

     

≥15 years

4

1.09

0.96 to 1.23

0.00%

0.714

<15 years

30

1.36

1.24 to 1.49

74.80%

<0.001

Study location

     

Unite States, Canada

21

1.39

1.24 to 1.56

53.20%

0.002

Europe

11

1.18

1.06 to 1.32

69.70%

<0.001

Asia

2

1.14

0.77 to 1.70

81.20%

0.021

Type of depression measurement

     

Self-reported scales

29

1.33

1.22 to 1.46

74.30%

<0.001

Clinical diagnosis

4

1.2

0.82 to 1.74

60.00%

0.058

Combined

1

1.12

0.89 to 1.41

NA

NA

  1. Abbreviations: NA, not applicable.
  2. *Five articles provided RRs for women and men separately, we pooled both risk estimates to obtain one overall estimates for the primary analysis; therefore, there are 27 reports in the primary analysis.
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BMC Psychiatry

ISSN: 1471-244X

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