Erratum: Neurobehavioral consequences of chronic intrauterine opioid exposure in infants and preschool children: a systematic review and meta-analysis

Table 1 Effect sizes and associated statistics for neurobehavioral domains in intrauterine opioid exposed infants and preschool children compared to others who have no history of intrauterine opioid exposure during pregnancy

Neuropsychological domains*	Studies¹	Effect size²	SE ³	N ⁴	Lower limit ⁵	Upper limit ⁶	Q ⁷	p f or Q ⁸	Z ⁹	p for Z ¹⁰	I² ¹¹	Fail safe N ¹²
INFANTS
Cognition	4	0.23	0.09	251	0.05	0.41	2.97	0.56	2.54	0.01	0.00	4
Psychomotor	4	0.43	0.09	251	0.25	0.60	5.36	0.25	4.65	0.00	25.41	25
Behavior	3	0.44	0.12	145	0.20	0.67	1.59	0.45	3.68	0.00	0.00	8
PRESCHOOL CHILDREN
Cognition	3	0.33	0.15	224	0.03	0.63	2.19	0.53	2.18	0.03	0.00	0
Psychomotor	3	0.58	0.15	224	0.28	0.88	6.36	0.09	3.78	0.00	52.84	31
*Behavior1**	2	1.31	0.33	160	0.67	1.95	5.96	0.02	3.99	0.00	83.21	np

¹= Number of studies used to calculate effect size, ²= Cohen’s d effect size, ³= Standard Error, ⁴=Total number of subjects in opioid exposed cohort ,⁵= Lower limit of the 95% confidence interval for the effect size,⁶= Upper limit of the 95% confidence interval for the effect size, ⁷= Q statistic: A test of homogeneity, ⁸= Probability that Q statistics significantly diff than 0, ⁹= One sample Z Statistic, ¹⁰= Probability that Z Statistics, is significantly diff than 0, ¹¹= I² statistics,¹²= Fail Safe N: a measure of publication bias, n/p= not possible since one needs more than 2 studies to perform this analysis, * All neuropsychological domains had fixed effects model employed except *1 where a random effect model was employed.

ISSN: 1471-244X