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Table 3 Correlations between ADMA, L-arginine:ADMA ratios, and markers of oxidatively generated DNA (8-oxodG), RNA (8-oxoGuo) and lipid (MDA) damage in all participants, healthy controls, and schizophrenia patients

From: Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case–control study

  8-oxodG 8-oxoGuo MDA
All participants    
ADMA −0.08 (−0.30 to 0.14) 0.01 (−0.21 to 0.22) −0.109 (−0.33 to 0.12)
L-arginine:ADMA ratio 0.07 (−0.16 to 0.28) −0.02 (−0.24 to 0.20) 0.07 (−0.17 to 0.29)
Healthy controls    
ADMA −0.11 (−0.41 to 0.21) −0.11 (0.41 to 0.20) −0.19 (−0.49 to 0.14)
L-arginine:ADMA ratio −0.07 (−0.38 to 0.24) −0.08 (−0.38 to 0.24) 0.12 (−0.22 to 0.43)
Schizophrenia patients    
ADMA −0.09 (−0.39 to 0.23) 0.08 (−0.24 to 0.38) −0.06 (−0.37 to 0.26)
L-arginine:ADMA ratio 0.16 (−0.16 to 0.45) 0.02 (−0.29 to 0.33) 0.04 (−0.28 to 0.35)
  1. Data are presented as Pearson correlation coefficients and corresponding 95% confidence intervals. Abbreviations:ADMA Asymmetric dimethyl arginine 8-oxodG 8-oxo-7,8-dihydro-2′-deoxyguanosine, 8-oxoGuo 8-oxo-7,8-dihydroguanosine MDA Malondialdehyde.