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Table 3 Correlations between ADMA, L-arginine:ADMA ratios, and markers of oxidatively generated DNA (8-oxodG), RNA (8-oxoGuo) and lipid (MDA) damage in all participants, healthy controls, and schizophrenia patients

From: Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case–control study

 

8-oxodG

8-oxoGuo

MDA

All participants

   

ADMA

−0.08 (−0.30 to 0.14)

0.01 (−0.21 to 0.22)

−0.109 (−0.33 to 0.12)

L-arginine:ADMA ratio

0.07 (−0.16 to 0.28)

−0.02 (−0.24 to 0.20)

0.07 (−0.17 to 0.29)

Healthy controls

   

ADMA

−0.11 (−0.41 to 0.21)

−0.11 (0.41 to 0.20)

−0.19 (−0.49 to 0.14)

L-arginine:ADMA ratio

−0.07 (−0.38 to 0.24)

−0.08 (−0.38 to 0.24)

0.12 (−0.22 to 0.43)

Schizophrenia patients

   

ADMA

−0.09 (−0.39 to 0.23)

0.08 (−0.24 to 0.38)

−0.06 (−0.37 to 0.26)

L-arginine:ADMA ratio

0.16 (−0.16 to 0.45)

0.02 (−0.29 to 0.33)

0.04 (−0.28 to 0.35)

  1. Data are presented as Pearson correlation coefficients and corresponding 95% confidence intervals. Abbreviations:ADMA Asymmetric dimethyl arginine 8-oxodG 8-oxo-7,8-dihydro-2′-deoxyguanosine, 8-oxoGuo 8-oxo-7,8-dihydroguanosine MDA Malondialdehyde.
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BMC Psychiatry

ISSN: 1471-244X

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