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Table 1 10 years risk of CVD calculated with Copenhagen risk score, WC = waist circumference, BP = blood pressure, RHR = resting heart rate, HDL = high density lipoprotein, non-HDL = total cholesterol-HDL, HbA1c = glycosylated haemoglobin, FEV1 = forced expiratory volume, VO 2max   = maximal oxygen uptake, sedentary = hours of physical activity during leisure time spending ≤1.5 metabolic equivalents, MVPA = hours of moderate or vigorous activity

From: Protocol for CHANGE: a randomized clinical trial assessing lifestyle coaching plus care coordination versus care coordination alone versus treatment as usual to reduce risks of cardiovascular disease in adults with schizophrenia and abdominal obesity

 

Variables

Expected difference, mean

Expected standard deviation

α

Power %

Primary outcome

10 years risk of CVD (%)

2.5

5.9

0.0166

0.90

Secondary outcomes

WC (cm)

5

14

0.0166

0.75

 

BP (mm Hg)

5

12

0.0166

0.88

 

RHR (per minutes)

10

20

0.0166

0.97

 

HDL (mmol/l)

0.2

0.4

0.0166

0.97

 

Non-HDL (mmol/l)

0.45

1.1

0.0166

0.87

 

HbA1c (mmol/mol)

0.5

1.1

0.0166

0.94

 

FEV1 (L)

-0.36

0.92

00166

0.84

 

VO2max

3.5

9

0.0166

0.73

 

Sedentary (minutes/day)

60

140

0.0166

0.90

 

MVPA (Minutes/day)

20

40

0.0166

0.97