| Study visit | 1 | 2 | 3 | 4 | 5 |
---|---|---|---|---|---|---|
 | Time point test | <7 d of first ECT | 1– 2 h before first ECT | 1– 2 h after first ECT | 7 – 14 d after last ECT | 6 mo after ECT-series |
 | Informed consent | X |  |  |  |  |
Diagnostic interview | MINI plus | X | Â | Â | Â | Â |
Clinical assessment | Clinical examination | X | Â | Â | Â | Â |
 | Illness history, previous episodes and ECT-treatment | X |  |  |  |  |
 | Current and concomitant medication | X |  |  | X | X |
Symptom severity | MADRS | X | Â | Â | X | X |
 | CGI | X |  |  | X | X |
Relapse | Interview | Â | Â | Â | Â | X |
Overall cognitive function | MMS | X | Â | Â | X | X |
Neuropsychological assessment | WASI | X | Â | Â | Â | X |
 | CVLT-II, Rey, Digit span from WASI-R, WCST, D-kefs: Color-Word interference test, Word fluency, Tower, TMT, CPT, Digit symbol WAIS-R, Pegboard | X |  |  | X | X |
Autobiographical memory | AMI-SF | X | Â | Â | X | X |
Everyday memory | EMQ | X | Â | Â | X | X |
Cognitive control | Dichotic listening | X | Â | Â | X | X |
Blood samples | Full blood, EDTA and PAX-gen for biobank | Â | X1) | X1) | X1) | X2) |
Radiology | MRI caput; T1 FSPGR, T2 CUBE FLAIR, RSI, SWI, MRS, MEGAPRESS | Â | X | X | X | X |