Skip to main content

Table 2 MTR-, ADC- and FA-map differences in patients with OCD compared to healthy control subjects

From: Obsessive-compulsive disorder is a heterogeneous disorder: evidence from diffusion tensor imaging and magnetization transfer imaging

Regions

Cluster size

t-value

MNI-space

P-value

   

x

y

z

SVC

Decreased regional FA in OCD patients compared with controls

Left sub-gyral WM

656

5.52

−39

−4

−19

0.001

Left medial frontal gyrus WM

472

4.95

−18

46

12

0.003

Left superior frontal gyrus WM

103

3.88

−11

58

22

0.035

Right inferior frontal gyrus WM

45

3.83

50

31

−9

0.038

Right superior temporal gyrus WM

75

3.77

60

−16

8

0.043

Right inferior frontal gyrus (BA 47) GM

74

3.97

56

22

−6

0.028

Right cuneus (BA 18) GM

88

4.10

13

 

10

0.021

Right postcentral gyrus (BA 3) GM

121

3.76

53

−17

39

0.044

Increased ADC-maps in patients with OCD compared with controls

Left sub-gyral WM

166

4.02

−37

−1

−23

0.024

Left inferior frontal gyrus WM

99

4.00

−36

26

−5

0.025

Left middle frontal gyrus WM

77

4.36

−27

20

43

0.010

Left middle occipital gyrus WM

74

3.95

−46

−70

−4

0.026

Left parahippocampal gyrus WM

61

4.13

−29

−29

−18

0.019

Right superior frontal gyrus (BA 10) GM

931

5.08

21

66

11

0.002

Left middle temporal gyrus (BA 21) GM

70

4.02

−62

−2

−3

0.024

Left inferior frontal gyrus (BA 47) GM

33

3.74

−28

17

−13

0.043

Increased MTR maps in OCD patients compared with controls

Left middle frontal gyrus

125

4.48

−39

24

43

0.008

Right inferior frontal gyrus (BA40)

58

4.46

51

25

5

0.008

  1. Cluster size = number of voxels; x,y,z = Coordinates (in mm) of significant local maxima are given for information in MNI space (Montreal Neurological Institute, http://www.bic.mni.mcgill.ca). BA: Brodmann area. For regions where an effect was hypothesized a small volume correction (SVC) was performed. P values are given after family wise error (FWE) correction for the particular volume