Obsessive-compulsive disorder is a heterogeneous disorder: evidence from diffusion tensor imaging and magnetization transfer imaging

Table 3 Brain regions showing significant correlations with clinical Y-BOCS subscores for obsessions and compulsions

Region	Clusterlevel	T-value	MNI-space			P-value
			x	y	z	SVC
Negative correlation between ADC-maps and Y-BOCS scores for compulsions in OCD.
Right sub-gyral	638	9.33	38	−1	−21	0.001
Left sub-gyral	4325	8.60	−30	16	18	0.001
Left anterior cingulate	547	7.41	−10	31	17	0.003
Left cingulate gyrus	257	6.20	−8	−36	31	0.010
Left lingual gyrus	347	6.00	−14	−68	−2	0.013
Left posterior cingulate	266	5.97	−3	−42	21	0.013
Left extra-nuclear	1637	5.96	−32	−6	25	0.013
Left lentiform nucleus	287	5.74	−11	−3	−2	0.017
Left insula (BA 13)	347	5.41	−31	−25	14	0.025
Positive correlation between MTI-maps and Y-BOCS scores for obsessions in OCD.
Left inferior parietal lobule WM	138	7.48	−54	−42	44	0.005
Left middle temporal gyrus (BA 39) GM	1051	9.25	−49	−61	22	0.001
Left Cuneus (BA 18) GM	195	5.63	−2	−79	20	0.030
Left Cerebellum/Culmen	103	5.35	−4	−47	−9	0.039

Cluster size = number of voxels; x,y,z = Coordinates (in mm) of significant local maxima are given for information in MNI space (Montreal Neurological Institute, http://www.bic.mni.mcgill.ca). BA: Brodmann area. For regions where an effect was hypothesized a small volume correction (SVC) was performed. P values are given after family wise error (FWE) correction for the particular volume.

ISSN: 1471-244X