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Table 3 Brain regions showing significant correlations with clinical Y-BOCS subscores for obsessions and compulsions

From: Obsessive-compulsive disorder is a heterogeneous disorder: evidence from diffusion tensor imaging and magnetization transfer imaging

Region Clusterlevel T-value MNI-space P-value
    x y z SVC
Negative correlation between ADC-maps and Y-BOCS scores for compulsions in OCD.
Right sub-gyral 638 9.33 38 −1 −21 0.001
Left sub-gyral 4325 8.60 −30 16 18 0.001
Left anterior cingulate 547 7.41 −10 31 17 0.003
Left cingulate gyrus 257 6.20 −8 −36 31 0.010
Left lingual gyrus 347 6.00 −14 −68 −2 0.013
Left posterior cingulate 266 5.97 −3 −42 21 0.013
Left extra-nuclear 1637 5.96 −32 −6 25 0.013
Left lentiform nucleus 287 5.74 −11 −3 −2 0.017
Left insula (BA 13) 347 5.41 −31 −25 14 0.025
Positive correlation between MTI-maps and Y-BOCS scores for obsessions in OCD.
Left inferior parietal lobule WM 138 7.48 −54 −42 44 0.005
Left middle temporal gyrus (BA 39) GM 1051 9.25 −49 −61 22 0.001
Left Cuneus (BA 18) GM 195 5.63 −2 −79 20 0.030
Left Cerebellum/Culmen 103 5.35 −4 −47 −9 0.039
  1. Cluster size = number of voxels; x,y,z = Coordinates (in mm) of significant local maxima are given for information in MNI space (Montreal Neurological Institute, http://www.bic.mni.mcgill.ca). BA: Brodmann area. For regions where an effect was hypothesized a small volume correction (SVC) was performed. P values are given after family wise error (FWE) correction for the particular volume.