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Table 4 In all cases, the outcome (Y) is ‘violent act’. X is the hypothesised determinant factor and M is the hypothesised mediating factor. See also Additional file 1 for figures representing these effects and pathways

From: Prospective cohort study of the relationship between neuro-cognition, social cognition and violence in forensic patients with schizophrenia and schizoaffective disorder

  C1: Direct effect X on Y before mediation C2: Direct effect X on Y after mediation A: Mediated effect X on Y via M B: Direct effect M on Y adjusted for X
M OR 95 % CI OR 95 % CI OR 95 % CI OR 95 % CI
  lower Upper lower Upper lower upper Lower upper
X = Neurocognitive composite 0.929 0.850 1.016          
social cognition     0.989 0.893 1.095 0.932 0.849 0.976 0.869 0.779 0.970
PANSS     0.955 0.836 1.092 0.947 0.821 0.994 1.069 1.016 1.125
SOFAS     1.008 0.904 1.124 0.916 0.788 0.997 0.931 0.882 0.982
HCR-20     0.972 0.881 1.072 0.950 0.831 0.997 1.214 1.058 1.393
X = social cognition 0.864 0.781 0.957          
neurocognition     0.869 0.779 0.970 0.997 0.934 1.031 0.989 0.893 1.095
PANSS     0.886 0.774 0.986 0.958 0.791 1.034 1.054 0.997 1.114
SOFAS     0.906 0.811 1.012 0.964 0.817 1.052 0.953 0.901 1.007
HCR-20     0.890 0.803 0.987 0.973 0.870 1.065 1.187 1.025 1.374
X = symptoms (PANSS total score) 1.067 1.017 1.120          
neurocognition     1.069 1.015 1.126 1.006 0.985 1.126 0.955 0.836 1.092
Social cognition     1.054 0.997 1.114 1.029 0.995 1.107 0.886 0.774 1.014
SOFAS     1.042 0.986 1.102 1.037 0.909 1.136 0.935 0.867 1.009
HCR-20     1.032 0.969 1.099 1.043 0.915 1.165 1.170 0.953 1.436
X = social function (SOFAS) 0.931 0.887 0.978          
Neurocognition     0.930 0.881 0.982 1.002 0.958 1.046 1.008 0.904 1.124
Social cognition     0.953 0.901 1.007 0.973 0.913 1.005 0.906 0.811 1.012
PANSS     0.935 0.867 1.009 0.972 0.866 1.092 1.042 0.986 2.633
HCR-20     0.971 0.920 1.024 0.942 0.753 1.008 1.320 1.095 1.614
X = violence proneness (HCR-20 total score) 1.228 1.075 1.403          
Neurocognition     1.214 1.058 1.393 1.012 0.956 1.085 0.972 0.881 1.072
Social cognition     1.187 1.027 1.371 1.055 1.000 1.166 0.890 0.797 0.987
PANSS     1.170 0.953 1.436 1.102 0.817 2.175 1.032 0.984 1.107
SOFAS     1.320 1.088 1.601 1.058 0.759 1.392 0.971 0.917 1.022
  1. Age and Gender as covariates. C1, C2, A and B refer to the labelling in Fig. 1. Confidence intervals underlined and in bold are significant