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Table 4 In all cases, the outcome (Y) is ‘violent act’. X is the hypothesised determinant factor and M is the hypothesised mediating factor. See also Additional file 1 for figures representing these effects and pathways

From: Prospective cohort study of the relationship between neuro-cognition, social cognition and violence in forensic patients with schizophrenia and schizoaffective disorder

 

C1: Direct effect X on Y before mediation

C2: Direct effect X on Y after mediation

A: Mediated effect X on Y via M

B: Direct effect M on Y adjusted for X

M

OR

95 % CI

OR

95 % CI

OR

95 % CI

OR

95 % CI

 

lower

Upper

lower

Upper

lower

upper

Lower

upper

X = Neurocognitive composite

0.929

0.850

1.016

         

social cognition

   

0.989

0.893

1.095

0.932

0.849

0.976

0.869

0.779

0.970

PANSS

   

0.955

0.836

1.092

0.947

0.821

0.994

1.069

1.016

1.125

SOFAS

   

1.008

0.904

1.124

0.916

0.788

0.997

0.931

0.882

0.982

HCR-20

   

0.972

0.881

1.072

0.950

0.831

0.997

1.214

1.058

1.393

X = social cognition

0.864

0.781

0.957

         

neurocognition

   

0.869

0.779

0.970

0.997

0.934

1.031

0.989

0.893

1.095

PANSS

   

0.886

0.774

0.986

0.958

0.791

1.034

1.054

0.997

1.114

SOFAS

   

0.906

0.811

1.012

0.964

0.817

1.052

0.953

0.901

1.007

HCR-20

   

0.890

0.803

0.987

0.973

0.870

1.065

1.187

1.025

1.374

X = symptoms (PANSS total score)

1.067

1.017

1.120

         

neurocognition

   

1.069

1.015

1.126

1.006

0.985

1.126

0.955

0.836

1.092

Social cognition

   

1.054

0.997

1.114

1.029

0.995

1.107

0.886

0.774

1.014

SOFAS

   

1.042

0.986

1.102

1.037

0.909

1.136

0.935

0.867

1.009

HCR-20

   

1.032

0.969

1.099

1.043

0.915

1.165

1.170

0.953

1.436

X = social function (SOFAS)

0.931

0.887

0.978

         

Neurocognition

   

0.930

0.881

0.982

1.002

0.958

1.046

1.008

0.904

1.124

Social cognition

   

0.953

0.901

1.007

0.973

0.913

1.005

0.906

0.811

1.012

PANSS

   

0.935

0.867

1.009

0.972

0.866

1.092

1.042

0.986

2.633

HCR-20

   

0.971

0.920

1.024

0.942

0.753

1.008

1.320

1.095

1.614

X = violence proneness (HCR-20 total score)

1.228

1.075

1.403

         

Neurocognition

   

1.214

1.058

1.393

1.012

0.956

1.085

0.972

0.881

1.072

Social cognition

   

1.187

1.027

1.371

1.055

1.000

1.166

0.890

0.797

0.987

PANSS

   

1.170

0.953

1.436

1.102

0.817

2.175

1.032

0.984

1.107

SOFAS

   

1.320

1.088

1.601

1.058

0.759

1.392

0.971

0.917

1.022

  1. Age and Gender as covariates. C1, C2, A and B refer to the labelling in Fig. 1. Confidence intervals underlined and in bold are significant
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BMC Psychiatry

ISSN: 1471-244X

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