| |
Left prefrontal cortex
|
Right prefrontal cortex
|
|---|
| |
Metabolite concentration (in IU) (CRLB)
|
Metabolite ratio (/Cre)
|
Metabolite concentration (in IU) (CRLB)
|
Metabolite ratio(/Cre)
|
|---|
|
Glx
|
5.673 (12 %)
|
1.129
|
7.424 (8 %)
|
1.576
|
|
Cre
|
5.023 (3 %)
|
1.0
|
4.710 (3 %)
|
1.0
|
|
t-Cho
|
1.238 (3 %)
|
0.246
|
1.217 (3 %)
|
0.258
|
|
NAA + NAAG
|
6.783 (3 %)
|
1.350
|
5.802 (3 %)
|
1.232
|
|
mI
|
3.815 (5 %)
|
0.760
|
3.295 (5 %)
|
0.699
|
- The MRS spectrum from the left prefrontal cortex shows lower concentrations of Glx compared with the opposite side. Glutamatergic hypometabolism correlated with a distinct hypometabolism in FDG-PET in this region; TR = 3000; TE = 30; NS = 64; voxel size = 8.0 mL. Abbreviations: CRLB = Cramér-Rao lower bounds; IU = Institutional Units; Glx = glutamate + glutamate; Cre = creatine; t-Cho = phosphorylcholine + glycerophosphorylcholine; NAA + NAAG = N-acetylaspartate + N-acetyl-aspartyl glutamate; mI = myo-inositol
