A randomized controlled trial of Mindfulness-Based Cognitive Therapy (MBCT) versus treatment-as-usual (TAU) for chronic, treatment-resistant depression: study protocol

Table 1 Overview of measures and corresponding measurement time points

Measure	Target concept	Baseline	FU1	FU2	FU3	FU4
IDS-SR	Depressive symptoms	●	●	●	●	●
MINI-depr. module	Diagnosis of major depression	●	●	●	●	●
WHOQOL-BREF	Quality of life	●	●	●	●	●
RRS-EXT	Rumination	●	●	●	●	●
FFMQ	Mindfulness skills	●	●	●	●	●
SCS	Self-compassion	●	●	●	●	●
MINI interview	Comorbid psychiatric disorders	●
DM-TRD	Treatment-resistance	●
CTQ	Childhood trauma	●

FU1: 2 weeks post intervention (MBCT + TAU)/8-12 weeks post baseline (TAU), FU2: 3 months post intervention (MBCT+ TAU)/2 weeks post intervention (TAU), FU3: 6 months post intervention (MBCT + TAU)/3 months post intervention(TAU), FU4: 6 months post intervention (TAU)