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Table 3 Differences in regions-of-interest (ROIs) between patients with bipolar disorder and patients with major depressive disorder after controlling for age, IQ and total intracranial volume

From: Distinguishing bipolar and major depressive disorders by brain structural morphometry: a pilot study

 

ROI

df

Mean in BD

Mean in MDD

t

p

p.adj (FDR)

Cortical (area.pial)

L bankssts

32.09

2.80E-07

2.31E-07

1.73

0.09

0.09

L precentral

29.01

1.33E-06

1.11E-06

1.83

0.08

0.09

L inferiorparietal

32.28

1.32E-06

1.09E-06

1.91

0.07

0.09

L superiorparietal

28.98

1.53E-06

1.17E-06

2.45

0.02

0.05

L precuneus

28.98

1.10E-06

8.56E-07

2.41

0.02

0.05

R middletemporal

27.53

9.76E-07

7.59E-07

2.43

0.02

0.05

Subcortical (volume)

L thalamus

25.72

1.99E-06

1.60E-06

1.95

0.06

0.08

L caudate nucleus

28.90

9.85E-07

8.13E-07

1.84

0.08

0.08

L putamen

26.15

1.70E-06

1.36E-06

1.99

0.06

0.08

L hippocampus

23.37

1.20E-06

9.15E-07

2.42

0.02

0.05

L amygdala

25.70

4.95E-07

3.83E-07

2.68

0.01

0.05

L nucleus accumbens

25.27

1.64E-07

1.17E-07

2.52

0.02

0.05

R thalamus

25.07

1.94E-06

1.60E-06

1.89

0.07

0.08

R caudate nucleus

27.58

1.01E-06

8.17E-07

1.89

0.07

0.08

R putamen

26.37

1.65E-06

1.31E-06

2.07

0.05

0.08

R hippocampus

24.94

1.24E-06

9.56E-07

2.57

0.02

0.05

R amygdala

27.23

5.03E-07

3.96E-07

2.44

0.02

0.05

R nucleus accumbens

28.10

1.84E-07

1.36E-07

2.47

0.02

0.05

  1. A ratio of each ROI was calculated to control for the individual variations of ICV, age and IQ. Ratio ROI mean value/(ICV * age * IQ estimate), df degree of freedom, p.adj (FDR) adjusted p-value, with false discovery rate corrected. BD Bipolar Disorder (n = 16), MDD Major Depressive Disorder (n = 19)