Table 2 Number of prescriptions, DDD and doses prescribed for the 11 most commonly prescribed antidepressant drugs
Dose prescribed (mg/day)c | ||||||||
|---|---|---|---|---|---|---|---|---|
Antidepressant drug | na | %b | DDD | Mode | Median | IQR | Min | Max |
Tricyclic and related antidepressants (TCA) | ||||||||
Amitriptyline hydrochloride | 236,416 | 7.27 | 75 | 25 | 25 | 15 to 50 | 2.0 | 350.0 |
Dosulepin hydrochloride | 125,302 | 3.85 | 150 | 75 | 75 | 50 to 150 | 12.5 | 325.0 |
Lofepramine | 47,414 | 1.46 | 105 | 140 | 140 | 140 to 210 | 35.0 | 350.0 |
Trazodone hydrochloride | 30,912 | 0.95 | 300 | 150 | 125 | 75 to 150 | 20.0 | 750.0 |
Selective serotonin reuptake inhibitors (SSRI) | ||||||||
Citalopram hydrobromide | 1,023,255 | 31.46 | 20 | 20 | 20 | 20 to 20 | 2.5 | 120.0 |
Escitalopram | 139,190 | 4.28 | 10 | 10 | 10 | 10 to 20 | 2.5 | 80.0 |
Fluoxetine hydrochloride | 778,285 | 23.93 | 20 | 20 | 20 | 20 to 20 | 4.0 | 120.0 |
Paroxetine hydrochloride | 159,389 | 4.90 | 20 | 20 | 20 | 20 to 30 | 4.0 | 100.0 |
Sertraline hydrochloride | 213,749 | 6.57 | 50 | 50 | 50 | 50 to 100 | 12.5 | 400.0 |
Other antidepressants | ||||||||
Mirtazapine | 142,400 | 4.38 | 30 | 30 | 30 | 15 to 45 | 3.8 | 112.5 |
Venlafaxine hydrochloride | 205,984 | 6.33 | 100 | 75 | 112.5 | 75 to 150 | 9.4 | 600.0 |
All other antidepressants | 66,553 | 2.05 | ||||||
Combined antidepressants | 83,784 | 2.58 | ||||||