Fig. 6

Brain regions most implicated in addiction. a Prefrontal cortex volume is shown to be reduced in those with SUD, produced via unpublished data with permission from Dr Samantha Brooks; b) A cartoon of the basal ganglia, associated with arousal, motivation, primary process affective states. Together, the prefrontal cortex and areas of the basal ganglia form the cortico-striatal pathway, which is implicated in the neuropathology of SUD and AN