The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample

Table 2 Assessment schedule (time in weeks)

	B	Stabilization						O	Maintenance
	-1	0	4	8	12	14	16	Q 2 wks × 8 wks then monthly visits	Cross over to Valproic Acid for mood episode on lithium
CGI-S-BP by doctor	X	X	X	X	X	X	X	X	X
Mood episode checklist	X	X	X	X	X	X	X	X	X
Consent	X
MINI- PLUS	X
Demographics/course of illness	X
HAM-A		X			X		X		X
MADRS		X	X		X		X	X	X
QIDS-SR 16	X	X	X	X	X	X	X	X	X
YMRS/CARS – M		X	X		X			X	X
Side Effects Survey	X	X	X	X	X	X	X	X	X
Q-LES-Q	X				X		X		X
IRS	X				X		X		X
MSSI	X	X	X		X		X		X
Serious Adverse Event Form	X	X	X	X	X		X	X	X

O observation phase, B baseline, ET Early Termination, Mini-PLUS Extended Mini-International Neuropsychiatric Interview, MADRS Montgomery Asberg Depression Rating Scale, QIDS-SR 16 Quick Inventory of Depressive Symptomatology Self-Report, YMRS Young Mania Rating Scale, CARS-M: Clinician Administered Rating Scale for Mania, HAM-A Hamilton Anxiety Rating Scale, CGI-BP Clinical Global Impressions of Severity - Bipolar Version, Q-LES-Q quality of life, enjoyment, and satisfaction questionnaire, IRS impulsivity rating scale, MSSI The Modified Scale of Suicidal Ideation

ISSN: 1471-244X