Skip to main content

Table 1 Characteristics of major depressive disorder (MDD) and healthy control (HC) groups

From: The influence of 5-HTTLPR and Val66Met polymorphisms on cortical thickness and volume in limbic and paralimbic regions in depression: a preliminary study

Characteristics MDD HC
N 43 15
Sex (F/M) 26/17 8/7
Age (yrs.) 30.3 ± 8.1 36.6 ± 11.1
5-HTTLPR polymorphysima LA/LA homozygotes = 8; S/S homozygotes = 14; S/LA heterozygotes = 20 LA/LA homozygotes = 5; S/S homozygotes = 3; S/LA heterozygotes = 7
Val66Met Val/Val homozygotes = 35; Met/- carriers = 8 (Met/Met = 1; Val/Met = 7) Val/Val homozygotes = 10; Met carriers = 5
Baseline HAMD17 21.4 ± 4.2 -
Duration of current MDE (yrs.) 4.4 ± 5.2 -
MDD onset (yrs.) 24.5 ± 10.9 -
  1. HAMD 17 Hamilton depression rating scale, MDD major depressive disorder
  2. Means ± SDs presented
  3. aS/S homozygotes: S/S, LG/S & LG/LG; S/LA heterozygotes: LA/S & LA/LG