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BMC Psychiatry

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Discovering biomarkers for antidepressant response: protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical characteristics of the first patient cohort

  • Raymond W. Lam1,
  • Roumen Milev2,
  • Susan Rotzinger3, 4,
  • Ana C. Andreazza4, 5,
  • Pierre Blier6,
  • Colleen Brenner7,
  • Zafiris J. Daskalakis4, 5,
  • Moyez Dharsee8,
  • Jonathan Downar3, 4,
  • Kenneth R. Evans8, 9,
  • Faranak Farzan4, 5,
  • Jane A. Foster3, 10,
  • Benicio N. Frey10,
  • Joseph Geraci3,
  • Peter Giacobbe3, 4,
  • Harriet E. Feilotter8, 9,
  • Geoffrey B. Hall10,
  • Kate L. Harkness11,
  • Stefanie Hassel12,
  • Zahinoor Ismail13,
  • Francesco Leri14,
  • Mario Liotti15,
  • Glenda M. MacQueen13,
  • Mary Pat McAndrews3,
  • Luciano Minuzzi10,
  • Daniel J. Müller4, 5,
  • Sagar V. Parikh16,
  • Franca M. Placenza3,
  • Lena C. Quilty4, 5,
  • Arun V. Ravindran4, 5,
  • Tim V. Salomons17,
  • Claudio N. Soares18,
  • Stephen C. Strother19,
  • Gustavo Turecki20, 21,
  • Anthony L. Vaccarino8,
  • Fidel Vila-Rodriguez1,
  • Sidney H. Kennedy3, 4, 18Email authorView ORCID ID profile and
  • on behalf of the CAN-BIND Investigator Team
BMC PsychiatryBMC series – open, inclusive and trusted201616:105

Received: 4 March 2016

Accepted: 18 March 2016

Published: 16 April 2016

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
4 Mar 2016 Submitted Original manuscript
Author responded Author comments
Resubmission - Version 2
Submitted Manuscript version 2
18 Mar 2016 Editorially accepted
16 Apr 2016 Article published 10.1186/s12888-016-0785-x

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

University of British Columbia and Vancouver Coastal Health Authority
Queen’s University, Providence Care
University Health Network
Department of Psychiatry, University of Toronto
Centre for Addiction and Mental Health
University of Ottawa Institute of Mental Health Research
Loma Linda University
Indoc Research
Department of Pathology and Molecular Medicine, Queen’s University
McMaster University, and St. Joseph’s Healthcare Hamilton
Department of Psychology, Queen’s University
Aston University
University of Calgary Hotchkiss Brain Institute
University of Guelph
Simon Fraser University
Universisty of Michigan
University of Reading
St. Michael’s Hospital
Rotman Research Institute at Baycrest Centre
McGill University
Douglas Mental Health University Institute Frank B. Common (FBC) F-3145