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Discovering biomarkers for antidepressant response: protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical characteristics of the first patient cohort

  • Raymond W. Lam1,
  • Roumen Milev2,
  • Susan Rotzinger3, 4,
  • Ana C. Andreazza4, 5,
  • Pierre Blier6,
  • Colleen Brenner7,
  • Zafiris J. Daskalakis4, 5,
  • Moyez Dharsee8,
  • Jonathan Downar3, 4,
  • Kenneth R. Evans8, 9,
  • Faranak Farzan4, 5,
  • Jane A. Foster3, 10,
  • Benicio N. Frey10,
  • Joseph Geraci3,
  • Peter Giacobbe3, 4,
  • Harriet E. Feilotter8, 9,
  • Geoffrey B. Hall10,
  • Kate L. Harkness11,
  • Stefanie Hassel12,
  • Zahinoor Ismail13,
  • Francesco Leri14,
  • Mario Liotti15,
  • Glenda M. MacQueen13,
  • Mary Pat McAndrews3,
  • Luciano Minuzzi10,
  • Daniel J. Müller4, 5,
  • Sagar V. Parikh16,
  • Franca M. Placenza3,
  • Lena C. Quilty4, 5,
  • Arun V. Ravindran4, 5,
  • Tim V. Salomons17,
  • Claudio N. Soares18,
  • Stephen C. Strother19,
  • Gustavo Turecki20, 21,
  • Anthony L. Vaccarino8,
  • Fidel Vila-Rodriguez1,
  • Sidney H. Kennedy3, 4, 18Email authorView ORCID ID profile and
  • on behalf of the CAN-BIND Investigator Team
BMC PsychiatryBMC series – open, inclusive and trusted201616:105

Received: 4 March 2016

Accepted: 18 March 2016

Published: 16 April 2016

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
4 Mar 2016 Submitted Original manuscript
Author responded Author comments
Resubmission - Version 2
Submitted Manuscript version 2
18 Mar 2016 Editorially accepted
16 Apr 2016 Article published 10.1186/s12888-016-0785-x

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

University of British Columbia and Vancouver Coastal Health Authority, Vancouver, Canada
Queen’s University, Providence Care, Kingston, Canada
University Health Network, Toronto, Canada
Department of Psychiatry, University of Toronto, Toronto, Canada
Centre for Addiction and Mental Health, Toronto, Canada
University of Ottawa Institute of Mental Health Research, Ottawa, Canada
Loma Linda University, Loma Linda, USA
Indoc Research, Toronto, Canada
Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Canada
McMaster University, and St. Joseph’s Healthcare Hamilton, Hamilton, Canada
Department of Psychology, Queen’s University, Kingston, Canada
Aston University, Birmingham, UK
University of Calgary Hotchkiss Brain Institute, Calgary, Canada
University of Guelph, Guelph, Canada
Simon Fraser University, Burnaby, Canada
Universisty of Michigan, Ann Arbor, USA
University of Reading, Reading, UK
St. Michael’s Hospital, Toronto, Canada
Rotman Research Institute at Baycrest Centre, Toronto, Canada
McGill University , Montréal, Canada
Douglas Mental Health University Institute Frank B. Common (FBC) F-3145, Montréal, Canada