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Table 1 Anthropometric measurements, selected clinical and laboratory variables, and self-report instruments in 275 postmenarcheal adolescent girls presenting with an eating disorder

From: Influence of premorbid BMI on clinical characteristics at presentation of adolescent girls with eating disorders

Premorbid BMI SDS class 1 2 3 4 5 p
N 11 60 100 79 25  
Prepubertal age (years) 7,5 ± 0,7 7,3 ± 1,0 7,3 ± 1,0 7,2 ± 0,8 7,4 ± 0,6 NS
Prepubertal BMI SDS −0,73 ± 0,76 −0,12 ± 0,79 0,60 ± 0,85 1,31 ± 0,78 1,76 ± 0,82 <0,001
Age at menarche (years) 13,4 ± 1,12 12,7 ± 1,0 12,6 ± 1,0 12,3 ± 0,9 12,4 ± 0,8 p = 0,002
Age at documented top weight (year) 15,4 ± 1,4 14,7 ± 1,3 14,7 ± 1,3 14,3 ± 1,4 14,3 ± 1,7 NS
BMI SDS at documented top weight −1,58 ± 0,62 −0,28 ± 0,47 0,62 ± 0,44 1,43 ± 0,35 2,35 ± 0,43 <0,001
BMI SDS change from prepuberty to top weight −0,83 ± 0,64 −0,21 ± 0,78 0,01 ± 0,82 0,17 ± 0,76 0,68 ± 0,80 <0,001
Age at presentation (years) 15,8 ± 1,3 15,4 ± 1,4 15,6 ± 1,3 15,3 ± 1,4 15,7 ± 1,4 NS
Gynecological age (years) 2,2 ± 1,5 2,7 ± 1,4 3,0 ± 1,4 3,0 ± 1,3 3,3 ± 1,4 NS
Duration of eating disturbed symptoms (months) 9 ± 12 9 ± 9 10 ± 10 10 ± 9 12 ± 11 NS
BMI SDS at presentation −2,79 ± 0,98 −1,60 ± 0,72 −0,61 ± 0,93 −0,13 ± 1,01 0,46 ± 1,11 <0,001
Weight loss (kg) 4,5 ± 3,8 5,0 ± 4,2 5,7 ± 4,9 9,5 ± 5,7 14,3 ± 7,9 <0,001
Rate of weight loss immediately preceding presentation (g/day) 74 ± 68 44 ± 62 31 ± 61 52 ± 66 60 ± 69 NS
Menstrual status (menses/amenorrhea/hormonal anticonception) 6/4/1 26/27/7 52/30/18 38/28/13 20/3/2 NS
(55/36/9 %) (43/45/12 %) (52/30/18 %) (48/36/16 %) (80/12/8 %)
Exercise as part of weight controlling behaviour 8 (73 %) 44 (73 %) 73 (73 %) 62 (79 %) 19 (76 %) NS
Vomiting as part of weight controlling behaviour 1 (9 %) 16 (27 %) 33 (33 %) 20 (25 %) 7 (28 %) NS
EDE-Q global score 1,7 ± 1,7 2,6 ± 1,5 3,3 ± 1,7 3,2 ± 1,6 3,1 ± 1,6 p = 0,012
EDE-Q eating concerns 1,7 ± 1,9 2,4 ± 1,8 2,9 ± 1,9 2,7 ± 1,8 2,6 ± 2,0 NS
EDE-Q restraint 1,3 ± 1,2 2,2 ± 1,4 2,7 ± 1,6 2,6 ± 1,5 2,6 ± 1,5 p = 0,021
EDE-Q shape concern 2,2 ± 2,2 3,2 ± 1,8 4,1 ± 1,8 4,0 ± 1,9 3,9 ± 1,8 p = 0,002
EDE-Q weight concern 1,8 ± 1,8 2,6 ± 1,7 3,4 ± 1,9 3,3 ± 1,8 3,2 ± 2,0 p = 0,011
MADRS-S 13 ± 11 16 ± 10 21 ± 11 17 ± 10 20 ± 12 p = 0,035
Diagnoses (AN/BN/EDNOS) 7/0/4 12/1/47 9/3/88 4/3/72 1/2/22 p < 0,001
(64/0/36 %) (20/2/78 %) (9/3/88 %) (5/4/91 %) (4/8/88 %)
Pulse rate 58 ± 9 61 ± 8 63 ± 7 62 ± 7 63 ± 8 NS
Systolic blood pressure 99 ± 8 105 ± 9 106 ± 10 108 ± 11 110 ± 10 p = 0,012
Plasma potassium (mmol/L) 4,3 ± 0,2 4,2 ± 0,3 4,2 ± 0,2 4,2 ± 0,3 4,3 ± 0,3 NS
Plasma phosphate (mmol/L) 1,18 ± 0,18 1,19 ± 0,17 1,19 ± 0,15 1,19 ± 0,15 1,21 ± 0,11 NS
Serum free triodothyronine (pmol/L) 3,5 ± 1,9 4,2 ± 1,3 4,2 ± 1,2 4,0 ± 1,2 4,0 ± 0,9 NS
Serum insulin-like growth factor 1 (μg/L) 227 ± 136 275 ± 116 308 ± 125 286 ± 132 310 ± 115 NS
Serum luteinizing hormone (IU/L) 0,43 ± 0,47 0,67 ± 0,74 0,89 ± 1,25 1,04 ± 1,53 0,86 ± 0,75 NS
  1. Patients are grouped in one SDS wide classes according to the BMI SDS at their highest weight before the onset of the eating disorder. Class 1 represents premorbid BMI SDS
  2. <−1,000, class 2 BMI SDS −1,000 - -0,001, class 3 BMI SDS 0–0,999, class 4 BMI SDS 1,000-1,999 and class 5 BMI SDS >1,999. Values are means ± SD. Statistical analyses are by one-sided ANOVA and Chi-square test for continuous and categorical variables, respectively
  3. Reference values for laboratory parameters: Plasma potassium 3,7-4,8 mmol//L, plasma phosphate 0,94–1,63 mmol/L, serum free triiodothyronine 3,9–7,7 pmol/L, serum insulin-like growth factor 1 115–510 μg/L for age 12–15 years and 247–482 μg/L for age 16–20 years, serum luteinizing hormone >1 IU/L throughout the menstrual cycle but highly variable
  4. BMI SDS BMI standard deviation score, AN anorexia nervosa, BN bulimia nervosa and subthreshold bulimia nervosa, EDNOS eating disorders not otherwise specified of restrictive subtype, EDE-Q eating disorders examination-questionnaire youth version; MADRS-S Montgomery-Åsberg depression rating scale-self report