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Table 1 Anthropometric measurements, selected clinical and laboratory variables, and self-report instruments in 275 postmenarcheal adolescent girls presenting with an eating disorder

From: Influence of premorbid BMI on clinical characteristics at presentation of adolescent girls with eating disorders

Premorbid BMI SDS class

1

2

3

4

5

p

N

11

60

100

79

25

 

Prepubertal age (years)

7,5 ± 0,7

7,3 ± 1,0

7,3 ± 1,0

7,2 ± 0,8

7,4 ± 0,6

NS

Prepubertal BMI SDS

−0,73 ± 0,76

−0,12 ± 0,79

0,60 ± 0,85

1,31 ± 0,78

1,76 ± 0,82

<0,001

Age at menarche (years)

13,4 ± 1,12

12,7 ± 1,0

12,6 ± 1,0

12,3 ± 0,9

12,4 ± 0,8

p = 0,002

Age at documented top weight (year)

15,4 ± 1,4

14,7 ± 1,3

14,7 ± 1,3

14,3 ± 1,4

14,3 ± 1,7

NS

BMI SDS at documented top weight

−1,58 ± 0,62

−0,28 ± 0,47

0,62 ± 0,44

1,43 ± 0,35

2,35 ± 0,43

<0,001

BMI SDS change from prepuberty to top weight

−0,83 ± 0,64

−0,21 ± 0,78

0,01 ± 0,82

0,17 ± 0,76

0,68 ± 0,80

<0,001

Age at presentation (years)

15,8 ± 1,3

15,4 ± 1,4

15,6 ± 1,3

15,3 ± 1,4

15,7 ± 1,4

NS

Gynecological age (years)

2,2 ± 1,5

2,7 ± 1,4

3,0 ± 1,4

3,0 ± 1,3

3,3 ± 1,4

NS

Duration of eating disturbed symptoms (months)

9 ± 12

9 ± 9

10 ± 10

10 ± 9

12 ± 11

NS

BMI SDS at presentation

−2,79 ± 0,98

−1,60 ± 0,72

−0,61 ± 0,93

−0,13 ± 1,01

0,46 ± 1,11

<0,001

Weight loss (kg)

4,5 ± 3,8

5,0 ± 4,2

5,7 ± 4,9

9,5 ± 5,7

14,3 ± 7,9

<0,001

Rate of weight loss immediately preceding presentation (g/day)

74 ± 68

44 ± 62

31 ± 61

52 ± 66

60 ± 69

NS

Menstrual status (menses/amenorrhea/hormonal anticonception)

6/4/1

26/27/7

52/30/18

38/28/13

20/3/2

NS

(55/36/9 %)

(43/45/12 %)

(52/30/18 %)

(48/36/16 %)

(80/12/8 %)

Exercise as part of weight controlling behaviour

8 (73 %)

44 (73 %)

73 (73 %)

62 (79 %)

19 (76 %)

NS

Vomiting as part of weight controlling behaviour

1 (9 %)

16 (27 %)

33 (33 %)

20 (25 %)

7 (28 %)

NS

EDE-Q global score

1,7 ± 1,7

2,6 ± 1,5

3,3 ± 1,7

3,2 ± 1,6

3,1 ± 1,6

p = 0,012

EDE-Q eating concerns

1,7 ± 1,9

2,4 ± 1,8

2,9 ± 1,9

2,7 ± 1,8

2,6 ± 2,0

NS

EDE-Q restraint

1,3 ± 1,2

2,2 ± 1,4

2,7 ± 1,6

2,6 ± 1,5

2,6 ± 1,5

p = 0,021

EDE-Q shape concern

2,2 ± 2,2

3,2 ± 1,8

4,1 ± 1,8

4,0 ± 1,9

3,9 ± 1,8

p = 0,002

EDE-Q weight concern

1,8 ± 1,8

2,6 ± 1,7

3,4 ± 1,9

3,3 ± 1,8

3,2 ± 2,0

p = 0,011

MADRS-S

13 ± 11

16 ± 10

21 ± 11

17 ± 10

20 ± 12

p = 0,035

Diagnoses (AN/BN/EDNOS)

7/0/4

12/1/47

9/3/88

4/3/72

1/2/22

p < 0,001

(64/0/36 %)

(20/2/78 %)

(9/3/88 %)

(5/4/91 %)

(4/8/88 %)

Pulse rate

58 ± 9

61 ± 8

63 ± 7

62 ± 7

63 ± 8

NS

Systolic blood pressure

99 ± 8

105 ± 9

106 ± 10

108 ± 11

110 ± 10

p = 0,012

Plasma potassium (mmol/L)

4,3 ± 0,2

4,2 ± 0,3

4,2 ± 0,2

4,2 ± 0,3

4,3 ± 0,3

NS

Plasma phosphate (mmol/L)

1,18 ± 0,18

1,19 ± 0,17

1,19 ± 0,15

1,19 ± 0,15

1,21 ± 0,11

NS

Serum free triodothyronine (pmol/L)

3,5 ± 1,9

4,2 ± 1,3

4,2 ± 1,2

4,0 ± 1,2

4,0 ± 0,9

NS

Serum insulin-like growth factor 1 (μg/L)

227 ± 136

275 ± 116

308 ± 125

286 ± 132

310 ± 115

NS

Serum luteinizing hormone (IU/L)

0,43 ± 0,47

0,67 ± 0,74

0,89 ± 1,25

1,04 ± 1,53

0,86 ± 0,75

NS

  1. Patients are grouped in one SDS wide classes according to the BMI SDS at their highest weight before the onset of the eating disorder. Class 1 represents premorbid BMI SDS
  2. <−1,000, class 2 BMI SDS −1,000 - -0,001, class 3 BMI SDS 0–0,999, class 4 BMI SDS 1,000-1,999 and class 5 BMI SDS >1,999. Values are means ± SD. Statistical analyses are by one-sided ANOVA and Chi-square test for continuous and categorical variables, respectively
  3. Reference values for laboratory parameters: Plasma potassium 3,7-4,8 mmol//L, plasma phosphate 0,94–1,63 mmol/L, serum free triiodothyronine 3,9–7,7 pmol/L, serum insulin-like growth factor 1 115–510 μg/L for age 12–15 years and 247–482 μg/L for age 16–20 years, serum luteinizing hormone >1 IU/L throughout the menstrual cycle but highly variable
  4. BMI SDS BMI standard deviation score, AN anorexia nervosa, BN bulimia nervosa and subthreshold bulimia nervosa, EDNOS eating disorders not otherwise specified of restrictive subtype, EDE-Q eating disorders examination-questionnaire youth version; MADRS-S Montgomery-Åsberg depression rating scale-self report
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BMC Psychiatry

ISSN: 1471-244X

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