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Table 2 Genes that resulted associated with remission (A) and response (B) in both the analyzed samples

From: Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway

   Korean sample STAR*D
Gene Gene full name SNPs with p < 0.05 SNPs (tot N) Permuted p SNPs with p < 0.05 SNPs (tot N) Permuted p
   N true N false / N true N false /
A        
AGBL1 ATP/GTP Binding Protein-Like 1 268 (7 %) 3454 (92 %) 3722 <0.00001 65 (9 %) 601 (90 %) 656 8.9e-5
CYB5A Cytochrome B5 Type A (Microsomal) 216 (58 %) 152 (41 %) 368 <0.00001 25 (37 %) 41 (62 %) 66 3.9e-5
MTRF1L Mitochondrial Translational Release Factor 1-Like 85 (47 %) 95 (52 %) 180 <0.00001 10 (38 %) 16 (61 %) 26 0.0003
RGS22 Regulator Of G-Protein Signaling 22 129 (29 % 311 (70 %) 440 <0.00001 25 (46 %) 29 (53 %) 104 0.0001
B          
CTNNA3 Catenin (Cadherin-Associated Protein), Alpha 3 446 (6 %) 6628 (93 %) 7074 <0.00001 118 (11 %) 952 (88 %) 1070 <0.00001
HS6ST3 Heparan Sulfate 6-O-Sulfotransferase 3 305 (15 %) 1626 (84 %) 1931 <0.00001 50 (14 %) 298 (85 %) 348 8.9e-5
  1. True/False are referred to the number (and percentage) of SNPs with p < 0.05 in the considered subset. The expected number (due to chance) of N true corresponds to 5 % of the total
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BMC Psychiatry

ISSN: 1471-244X

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