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Table 2 Genes that resulted associated with remission (A) and response (B) in both the analyzed samples

From: Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway

  

Korean sample

STAR*D

Gene

Gene full name

SNPs with p < 0.05

SNPs (tot N)

Permuted p

SNPs with p < 0.05

SNPs (tot N)

Permuted p

  

N true

N false

/

N true

N false

/

A

       

AGBL1

ATP/GTP Binding Protein-Like 1

268 (7 %)

3454 (92 %)

3722

<0.00001

65 (9 %)

601 (90 %)

656

8.9e-5

CYB5A

Cytochrome B5 Type A (Microsomal)

216 (58 %)

152 (41 %)

368

<0.00001

25 (37 %)

41 (62 %)

66

3.9e-5

MTRF1L

Mitochondrial Translational Release Factor 1-Like

85 (47 %)

95 (52 %)

180

<0.00001

10 (38 %)

16 (61 %)

26

0.0003

RGS22

Regulator Of G-Protein Signaling 22

129 (29 %

311 (70 %)

440

<0.00001

25 (46 %)

29 (53 %)

104

0.0001

B

         

CTNNA3

Catenin (Cadherin-Associated Protein), Alpha 3

446 (6 %)

6628 (93 %)

7074

<0.00001

118 (11 %)

952 (88 %)

1070

<0.00001

HS6ST3

Heparan Sulfate 6-O-Sulfotransferase 3

305 (15 %)

1626 (84 %)

1931

<0.00001

50 (14 %)

298 (85 %)

348

8.9e-5

  1. True/False are referred to the number (and percentage) of SNPs with p < 0.05 in the considered subset. The expected number (due to chance) of N true corresponds to 5 % of the total