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Table 2 Characteristics of the studies included in the review

From: Cardiovascular risk assessment in patients with a severe mental illness: a systematic review and meta-analysis

Author, year

Study design

Country

Setting

Diagnosis

Diagnostic criteria

Psychiatric Group

Comparative Group

 

Number

Age [mean(SD)]

FRS [mean (SD)]

SCORE [mean (SD)]

Number

Age [mean(SD)]

FRS [mean (SD)]

        

CVD

Stroke

CHD

   

CVD

Stroke

CHD

Acharya T, 2013 [43]

Retrospective cross-sectional

USA

Hospital

Depressive disorder

Not reported

1.136

60.1 (3.0)

  

By drug

 

472

61,4 (11.9)

  

17.1 (5.7)

Allan CL, 2011 [22]

Cross-sectional

UK

Primary & secondary care services

Depressive disorder

DSM IV

36

71.8 (7.7)

 

10.3 (7.6)

  

25

71.8 (7.3)

 

10.1 (7.7)

 

Arango C, 2008 [44]

Cross-sectional

Spain

Secondary services

Schizophrenia & related disorders

DSM IV

1.452

40.7 (12.2)

  

6.8 (6.9)

0.9 (1.9)

     

Bernardo M, 2009 [45]

Cross-sectional

Spain

Psychiatric hospital

Schizophrenia

DSM IV

733

37.8 (11.3)

         

Cohn T, 2004 [37]

Cross-sectional

Canada

Psychiatric hospital & secondary services

Schizophrenia & related disorders

DSM IV

240

43.6 (1.3)

    

7,020

43.6 (1.3)

   

Correll CU, 2006 [46]

Cross-sectional

USA

Psychiatric hospital

Psychiatric diagnosis

Not reported

367

42.9 (15.3)

         

Correll CU, 2011 [47]

Cross-sectional

USA

Psychiatric hospital

Psychiatric diagnosis

Not reported

127

39.3 (14.9)

  

2.5 (4.2)

      

Daumit GL, 2008 [48]

RCT

USA

Secondary services

Schizophrenia

DSM IV

1.125

40.7 (11.1)

  

8.5 (7.4)

      

Dickerson FB, 2013 [49]

RCT

USA

Secondary services

SMI

DSM IV

291

          

Druss BG, 2010 [50]

RCT

USA

Secondary services

SMI

Not reported

407

          

Ferreira L, 2010 [51]

Case-control

Portugal

Secondary services

Schizophrenia

DSM IV

125

41.0 (11.0)

    

1,721

41.0 (12.0)

   

Foguet-Boreu Q, 2013 [32]

Cross-sectional

Spain

Secondary services

SMI

Not reported

137

51.1 (12.9)

         

Garcia-Portilla MP, 2009 [52]

Cross-sectional

Spain

Secondary services

Bipolar disorders

ICD10

194

46.6

  

7.6 (7.4)

1.8 (4.4)

     

Goodrich DE, 2012 [53]

RCT

USA

Secondary services

Schizophrenia

Not reported

134

52.8 (9.9)

         

Goff DC, 2005 [24]

Case-control

USA

Secondary services

Schizophrenia

DSM IV

689

40.4 (11.2)

    

687

40.4 (11.2)

  

6.5

Grover S, 2014 [54]

Cross-sectional

India

Hospital

Bipolar disorder

ICD10

105

39.6 (13.1)

  

3.4 (5.0)

1.7 (1.8)

     

Hoffman BM, 2010 [55]

RCT

USA

H ospital

Depressive disorder

DSM IV

46

53.4 (7.0)

14.0 (9.0) Only males.

        

Jin H, 2011 [56]

Cross-sectional

USA

Secondary services

With psychotic symptoms

DSM IV

179

63.1

         

Mackin P, 2007 [25]

Case-control

UK

Secondary services

Psychiatric diagnosis

Not reported

90

45.7 (11.8)

11.3 (12.3)

1.7 (3.2)

9.3 (10.5)

 

92

43.5 (13.6)

6.8 (6.4)

1.0 (1.1)

4.7 (4.3)

Margari F, 2013 [26]

Cross-sectional

Italy

Psychiatric hospital

Psychiatric diagnosis

DSM IV

83

47.0 (9.0)

8.3 (5.8)

   

77

52.0 (8.6)

10.7 (5.9)

  

McCreadie RG, 2003 [27]

Cross-sectional

UK

Secondary services

Schizophrenia

DSM IV

102

45.0 (13.0)

  

9.5 (7.6)

     

4.1 (4.0)

McLean G, 2014 [23]

Cross-sectional

UK

Primary care

Schizophrenia & related disorders

Read code

1.942

     

215,165

    

Nurjono M, 2014 [57]

Cross-sectional

Singapore

Psychiatric hospital

Schizophrenia

DSM IV

64

          

Osborn DP, 2006 [36]

Cross-sectional

UK

Primary care

SMI

Not reported

74

     

148

    

Protopopova D, 2012 [58]

Cross-sectional

Czech Republic

Psychiatric hospital

Schizophrenia & pychoses

ICD10

129

36.0 (11.9)

         

Ratliff JC, 2013 [28]

Case-control

USA

Secondary services

Schizophrenia & related disorders

DSM IV

115

47.5 (8.3)

10.7

   

197

47.7 (8.5)

8.5

  

Said MA, 2012 [59]

Cross-sectional

Malaysia

Hospital

Schizophrenia

DSM IV

270

   

6.3 (5.6)

      

Stroup TS, 2013 [60]

RCT

USA

Secondary services

Schizophrenia & related disorders.

Not reported

215

41.1 (11.1)

  

7.3 (5.7)

      

Sicras-Mainar A, 2013 [61]

Cross-sectional

Spain

Primary, secondary & hospital care services

Schizophrenia & related disorders

DSM IV

705

48.2 (15.8)

11.9 (5.7)

        

Slomka JM, 2012 [62]

RCT

USA

Secondary services

Bipolar disorder

Not reported

118

53.0 (9.9)

13.7 (10.0)

        

Smith PJ, 2007 [63]

RCT

USA

Not reported

Depressive disorder

DSM IV

198

51.6 (7.5)

  

5.4 (3.2)

      

Tay YH, 2013 [29]

Cross-sectional

China

Secondary services

Schizophrenia

DSM IV

83

36.2 (7.7)

4.7 (4.7)

   

243

34.6 (8.2)

3.1 (3.2)

  

Taylor V, 2010 [64]

Case-control

Canada

Secondary services

Bipolar disorder & major depressive disorder

DSM IV

54

25.9 (7.0)

    

104

    

Wysokiński A, 2012 [65]

Retrospective review

Poland

Psychiatric hospital

Psychotic disorder

ICD10

62

38.0 (12.4)

6.4 (7.2)

3.7 (2.8)

5.8 (6.1)

      

Zuidersma M, 2015 [66]

Cross-sectional

Netherlands

Primary & secondary care services

Depressive disorder

DSM IV

352

70.7 (7.4)

5.8 (3.8)

        
  1. Abbreviations: FRS Framingham risk score, CVD cardiovascular disease, CHD cardiovascular heart disease, MI myocardial infarction, SCORE systematic coronary risk evaluation, NE: SMI severe mental illness, DSM-IV diagnostic and statistical manual of mental disorders, 4th Edition, ICD-10 International classification of diseases, 10th revision, RCT randomized controlled trial