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Table 2 Analysis of outcomes

From: Results of a pilot cluster randomised trial of the use of a Medication Review Tool for people taking antipsychotic medication

 

Treatment as usual

Medication review tool

Coefficient or OR (95 % CI)

 

Baseline

Follow-up

Baseline

Follow-up

 

Outcome

     

Decision Self Efficacy Scale (mean, SD)

29 (9)

32 (10)

29 (10)

30 (9)

-4.16 (-9.81, 1.49)

Drug Attitude Inventory (mean, SD)

5 (4)

3 (4)

5 (4)

5 (3)

1.65 (-0.09, 3.40)

LUNSERS (mean, SD)

38 (23)

28 (19)

38 (23)

30 (20)

-0.42 (-8.12, 7.29)

Brief PANSS (mean, SD)

18 (7)

16 (7)

17 (7)

16 (6)

0.13 (-2.21, 2.48)

Client Satisfaction Questionnaire (mean, SD)

 

28 (5)

 

27 (5)

-0.29 (-3.04, 2.45)a

Medication Adherence Questionnaire (median, IQR)

0 (0, 1)

1 (0, 1)

0 (0, 0)

0 (0, 1)

-0.44 (-0.76, -0.11)

2 or more antipsychotics taken (n/N, %)

7/29 (24)

7/24 (29)

4/31 (13)

7/26 (27)

0.89 (0.26, 3.08)b

Dose (chlorpromazine equivalents) (median, IQR)

400 (200, 600)

350 (200, 648)

250 (132, 400)

292 (200, 462)

-26.02 (-97.23, 45.20)

Change in chlorpromazine equivalent baseline-FU (median, IQR)

 

0 (0, 50)

 

0 (-64, 65)

3.33 (-78.12, 84.79)

  1. Abbreviations: SD standard deviation, LUNSERS Liverpool University neuroleptic side effect rating scale, PANSS positive and negative syndrome scale, IQR interquartile range, FU follow-up, OR odds ratio
  2. aThere is no baseline adjustment for this analysis
  3. bOdds ratio. Data were too sparse to do the adjusted analysis