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Table 1 Risks of psychiatric disorders, suicide attempt and suicide in individuals with EDS compared with matched comparison individuals

From: Nationwide population-based cohort study of psychiatric disorders in individuals with Ehlers–Danlos syndrome or hypermobility syndrome and their siblings

  EDS individuals (n = 1,771) Matched comparison individuals (n = 17,710)   
  n (%) n (%) RR (95 % CI) RRa (95 % CI)
Autism spectrum disorder 52 (2.9) 72 (0.4) 7.4 (5.2–10.7) 8.4 (5.7–12.4)
Bipolar disorder 15 (0.9) 56 (0.3) 2.7 (1.5–4.7) 2.6 (1.4–4.7)
ADHD 76 (4.3) 144 (0.8) 5.6 (4.2–7.4) 5.8 (4.3–7.9)
Depression 197 (11.1) 643 (3.6) 3.4 (2.9–4.1) 3.5 (2.9–4.2)
Suicide attempt 96 (5.4) 464 (2.6) 2.1 (1.7–2.7) 2.1 (1.6–2.6)
Suicide 2 (0.1) 6 (0.03) 3.3 (0.7–16.5) 2.9 (0.6–14.4)
Schizophrenia 3 (0.2) 38 (0.2) 0.8 (0.2–2.6) 0.6 (0.1–2.5)
  1. Associations are expressed as risk ratios (RR) and 95 % confidence intervals (95 % CIs) from conditional logistic regression
  2. Note: statistically significant RR are bolded. RRa, risk ratios restricted to individuals born in Sweden