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Table 3 Risks of psychiatric disorders, suicide attempt and suicide in individuals with hypermobility syndrome (including EDS) compared with matched comparison individuals

From: Nationwide population-based cohort study of psychiatric disorders in individuals with Ehlers–Danlos syndrome or hypermobility syndrome and their siblings

  Hypermobility syndrome individuals (n = 10,019) Matched comparison individuals (n = 100,190)   
  n (%) n (%) RR (95 % CI) RRa (95 % CI)
Autism spectrum disorder 161 (1.6) 1,186 (1.2) 1.4 (1.1–1.6) 1.3 (1.1–1.6)
Bipolar disorder 42 (0.4) 296 (0.3) 1.4 (1.1–2.0) 1.4 (0.9–1.9)
ADHD 301 (3.0) 546 (0.5) 5.8 (5.0–6.7) 5.5 (4.8–6.4)
Depression 696 (7.0) 3,180 (3.2) 2.3 (2.1–2.5) 2.3 (2.1–2.5)
Suicide attempt 423 (4.2) 2,121 (2.2) 2.1 (1.8–2.3) 2.0 (1.8–2.3)
Suicide 6 (0.1) 3 (0.05) 1.8 (0.8–4.4) 1.9 (0.7–5.0)
Schizophrenia 11 (0.1) 159 (0.2) 0.7 (0.4–1.3) 0.7 (0.4–1.3)
  1. Associations are expressed as risk ratios (RR) and 95 % confidence intervals (95 % CIs) from conditional logistic regression
  2. Note: statistically significant RR are bolded. RRa, risk ratios restricted to individuals born in Sweden