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Table 4 Risks of psychiatric disorders, suicide attempt and suicide in siblings of individuals with hypermobility syndrome (hypermobility syndrome siblings) compared with matched siblings to individuals without hypermobility syndrome (comparison siblings)

From: Nationwide population-based cohort study of psychiatric disorders in individuals with Ehlers–Danlos syndrome or hypermobility syndrome and their siblings

  Hypermobility syndrome siblings (n = 11,082) Comparison siblings (n = 108,772)   
  n (%) n (%) RR (95 % CI) RRa (95 % CI)
Autism spectrum disorder 66 (0.6) 500 (0.5) 1.3 (1.1–1.7) 1.3 (1.1–1.7)
Bipolar disorder 31 (0.3) 269 (0.3) 1.1 (0.8–1.6) 1.2 (0.8–1.7)
ADHD 124 (1.1) 966 (0.9) 1.3 (1.1–1.5) 1.3 (1.1–1.5)
Depression 343 (3.1) 2,788 (2.6) 1.2 (1.1–1.3) 1.2 (1.1–1.3)
Suicide attempt 270 (2.4) 2,182 (2.0) 1.2 (1.1–1.4) 1.2 (1.1–1.4)
Suicide 29 (0.3) 230 (0.2) 1.2 (0.9–1.7) 1.3 (0.9–1.8)
Schizophrenia 26 (0.2) 184 (0.2) 1.4 (0.9–2.0) 1.3 (0.9–1.9)
  1. Associations are expressed as risk ratios (RR) and 95 % confidence intervals (95 % CIs) from conditional logistic regression
  2. Note: statistically significant RR are bolded. RRa, risk ratios restricted to individuals born in Sweden