Table 2 Linear mixed model analyses for long-term disability (total score WHODAS-II)^a

Baseline psychiatric status

 Healthy controls

Ref

Ref

Ref

Ref

 SAD

15.28 (1.55)

<.001

14.26 (1.74)

<.001

5.09 (1.42)

<.001

4.38 (1.55)

<.001

 SAD x time

-6.48 (0.61)

<.001

-6.40 (0.61)

<.001

-2.52 (0.57)

.01

-2.56 (0.57)

.01

 PDA

9.31 (2.09)

<.001

9.54 (2.24)

<.001

-0.46 (1.88)

.65

-0.65 (1.98)

.52

 PDA x time

-4.18 (0.85)

<.001

-4.04 (0.85)

<.001

-0.07 (0.77)

.94

-0.11 (0.77)

.92

 PD

5.96 (2.15)

<.001

6.40 (2.29)

<.001

0.46 (1.84)

.65

0.23 (1.94)

.82

 PD x time

-1.43 (0.88)

.15

-1.29 (0.88)

.20

-0.07 (0.77)

.95

-0.11 (0.77)

.92

 GAD

13.01 (1.93)

<.001

13.19 (2.07)

<.001

6.62 (1.68)

<.001

6.07 (1.77)

<.001

 GAD x time

-5.80 (0.79)

<.001

-5.58 (0.80)

<.001

-3.52 (0.70)

<.001

-3.55 (0.70)

<.001

 Multiple AD

20.93 (1.57)

<.001

18.21 (1.58)

<.001

3.58 (1.46)

<.001

3.00 (1.58)

.003

 Multiple AD x time

-7.61 (0.54)

<.001

-7.54 (0.54)

<.001

-1.31 (0.58)

.19

-1.36 (0.58)

.18

Psychiatric course trajectory

 Healthy controls

Ref

Ref

Ref

 Remission

10.30 (0.82)

<.001

-3.12 (1.12)

.002

0.63 (0.84)

.53

 Recurrence

7.82 (1.66)

<.001

-0.01 (1.70)

.99

0.42 (1.23)

.67

 Chronic course

14.65 (1.32)

<.001

3.65 (1.48)

<.001

0.94 (1.08)

.35

Symptom dimensions

 Anxiety arousal

24.28 (0.04)

<.001

12.49 (0.06)

<.001

12.51 (0.06)

<.001

 Anxiety arousal x time

1.49 (0.02)

.14

0.90 (0.03)

.37

0.86 (0.03)

.39

 Avoidance behaviour

23.28 (0.02)

<.001

10.58 (0.03)

<.001

10.57 (0.03)

<.001

 Avoidance behaviour x time

-1.40 (0.01)

.16

0.17 (0.01)

.87

0.14 (0.01)

.89