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Table 2 Results of ANCOVAs examining group differences on primary and secondary variables at pre, post and 20 week follow up

From: A pilot randomized controlled trial of a tailored cognitive behavioural therapy based intervention for depressive symptoms in those newly diagnosed with multiple sclerosis

  Pre Post Pre to post 20 week fup Pre to fup
Variable Mean (SD) Mean (SD) F (df = 1,29) d (95% CI) Mean (SD) F (df = 1,29) d (95% CI)
BDI-2
 CBT 29.80 (11.40) 10.89 (6.19)    9.33 (7.89)   
 TAU 28.53 (12.21) 25.40 (10.31) 29.17*** 1.66 (0.83, 2.49) 24.34 (13.54) 18.43*** 1.34 (0.54, 2.13)
STAI
 CBT 45.40 (6.26) 33.87 (6.88)    36.20 (10.77)   
 TAU 48.86 (11.20) 50.46 (12.22) 28.67*** 1.63 (0.80, 2.45) 45.67 (14.15) 2.95 0.73 (− 0.01, 1.47)
MFIS
 CBT 12.13 (3.58) 8.73 (3.58)    8.06 (3.03)   
 TAU 12.26 (3.84) 11.93 (4.38) 5.89* 0.78 (0.04, 1.52) 11.06 (4.74) 11.16** 0.73 (− 0.01, 1.47)
PES
 CBT 17.06 (5.62) 12.53 (6.18)    11.26 (4.51)   
 TAU 18.80 (6.57) 17.67 (7.05) 3.92* 0.75 (0.01, 1.49) 16.80 (5.91) 9.80** 1.03 (0.26, 1.79)
MSQOL mental
 CBT 36.06 (14.81) 63.13 (14.42)    69.93 (19.64)   
 TAU 40.06 (17.35) 44.20 (21.05) 12.73*** 1.03 (0.26, 1.79) 49.27 (20.49) 12.28** 1.00 (0.24,1.76)
MSQOL physical
 CBT 47.39 (18.07) 65.92 (14.66)    63.32 (17.25)   
 TAU 43.28 (17.63) 47.74 (19.07) 18.26*** 1.04 (0.28, 1.80) 49.33 (21.32) 7.85** 0.70 (−0.03, 1.44)
PSQI
 CBT 9.00 (3.46) 4.40 (2.09)    4.80 (2.54)   
 TAU 9.06 (3.93) 7.87 (2.99) 22.02*** 1.31 (0.52, 2.10) 8.20 (3.60) 11.06** 1.06 (0.30,1.83)
PSSS
 CBT 63.73 (16.41) 59.46 (13.45)    62.26 (20.39)   
 TAU 69.40 (12.10) 57.33 (12.48) 15.51** 0.96 (0.20, 1.71) 58.86 (17.31) 0.001 0.17 (−0.54, 0.89)
RSA
 CBT 137.29 (34.38) 165.45 (26.30)    164.10 (25.95)   
 TAU 146.40 (32.38) 148.25 (32.63) 17.98*** 0.57 (−0.16, 1.30) 149.53 (37.84) 8.49** 0.44 (−0.29, 1.16)
Acceptance
 CBT 30.40 (6.04) 28.20 (3.89)    27.93 (3.88)   
 TAU 32.13 (4.82) 31.14 (4.78) 2.18 0.66 (−0.09, 1.41) 31.40 (5.96) 3.01 −0.67 (−1.39,0.08)
Problem solving
 CBT 6.76 (3.19) 8.87 (3.54)    8.93 (3.53)   
 TAU 6.73 (4.10) 8.73 (4.31) 0.09 −0.46 (−1.19,0.26) 6.81 (3.97) 3.99* 0.55 (−0.18,1.28)
Avoidance
 CBT 9.87 (4.99) 4.20 (3.07)    3.93 (2.96)   
 TAU 8.53 (5.22) 7.40 (4.45) 11.27** 0.81 (0.05, 1.53) 7.87 (5.24) 9.75** 0.90 (0.13, 1.62)
  1. FU 20 week follow up, ns not significant, CBT tailored CBT intervention, TAU treatment as usual, BDI Beck Depression Inventory –II, STAI State Trait Anxiety Inventory, MFIS Modified Fatigue Impact Scale, PES Pain Effects Scale, MSQOL mental Multiple Sclerosis Quality of Life-mental health summary score, MSQOL physical Multiple Sclerosis Quality of Life-physical health summary score, PSQI Pittsburgh Sleep Quality Index, PSSS Perceived Social Support Scale, RSA Resilience Scale for Adults, Acceptance Acceptance of Chronic Health Conditions Scale, Problem solving Ways of coping questionnaire – planful problem-solving subscale, Avoidance Ways of coping questionnaire – escape-avoidance subscale
  2. *p < .05, **p < .01; ***p < .001