Table 2 Progression of lowest neutrophil count to agranulocytosis
Lowest neutrophil count (excluding counts taken during episode of agranulocytosis) | Amber: Mild neutropenia 1500-1900/mm3 | Red: Moderate neutropenia 1000-1400/mm3 | Severe neutropenia 500-900/mm3 |
|---|---|---|---|
n = 24 | n = 8 | n = 2 | |
One year after lowest level of neutropenia | |||
Still on Clozapine | 22 | 6 | 0 |
Clozapine discontinued | 2 | 2 | 1 |
Developed agranulocytosis (and then discontinued) | 0 | 0 | 1 |
Clozapine and agranulocytosis status unknown | 0 | 0 | 0 |
Three years after lowest level of neutropenia | |||
Still on Clozapine | 18 | 4 | 0 |
Clozapine discontinued | 3 | 2 | 1 |
Developed agranulocytosis (and then discontinued) | 0 | 0 | 1 |
Clozapine and agranulocytosis status unknown | 3 | 2 | 0 |