TY - JOUR AU - Elkis, H. PY - 2007 DA - 2007// TI - Treatment-resistant schizophrenia JO - Psychiatr Clin North Am VL - 30 UR - https://doi.org/10.1016/j.psc.2007.04.001 DO - 10.1016/j.psc.2007.04.001 ID - Elkis2007 ER - TY - JOUR AU - Farooq, S. AU - Agid, O. AU - Foussias, G. AU - Remington, G. PY - 2013 DA - 2013// TI - Using treatment response to subtype schizophrenia: proposal for a new paradigm in classification JO - Schizophr Bull VL - 39 UR - https://doi.org/10.1093/schbul/sbt137 DO - 10.1093/schbul/sbt137 ID - Farooq2013 ER - TY - JOUR AU - Agid, O. AU - Arenovich, T. AU - Sajeev, G. AU - Zipursky, R. B. AU - Kapur, S. AU - Foussias, G. AU - Remington, G. PY - 2011 DA - 2011// TI - An algorithm-based approach to first-episode schizophrenia: response rates over 3 prospective antipsychotic trials with a retrospective data analysis JO - J Clin Psychiatry VL - 72 UR - https://doi.org/10.4088/JCP.09m05785yel DO - 10.4088/JCP.09m05785yel ID - Agid2011 ER - TY - JOUR AU - Kolakowska, T. AU - Williams, A. O. AU - Ardern, M. AU - Reveley, M. A. AU - Jambor, K. AU - Gelder, M. G. AU - Mandelbrote, B. M. PY - 1985 DA - 1985// TI - Schizophrenia with good and poor outcome, I: early clinical features, response to neuroleptics and signs of organic dysfunction JO - Br J Psychiatry VL - 146 UR - https://doi.org/10.1192/bjp.146.3.229 DO - 10.1192/bjp.146.3.229 ID - Kolakowska1985 ER - TY - JOUR AU - May, P. R. A. AU - Putten, T. AU - Yale, C. PY - 1980 DA - 1980// TI - Predicting outcome of antipsychotic drug treatment from early response JO - Am J Psychiatry VL - 137 UR - https://doi.org/10.1176/ajp.137.9.1088 DO - 10.1176/ajp.137.9.1088 ID - May1980 ER - TY - JOUR AU - Kane, J. M. AU - Honigfeld, G. AU - Singer, J. PY - 1988 DA - 1988// TI - Clozapine for the treatment resistant schizophrenic: a double-blind comparison versus chlorpromazine/benztropine JO - Arch Gen Psychiatry VL - 45 UR - https://doi.org/10.1001/archpsyc.1988.01800330013001 DO - 10.1001/archpsyc.1988.01800330013001 ID - Kane1988 ER - TY - STD TI - Psychosis and schizophrenia in adults: treatment and management. NICE clinical guideline 178. 2014. Available at www.nice.org.uk/CG178 [NICE guideline]. UR - http://www.nice.org.uk/CG178 ID - ref7 ER - TY - JOUR AU - Lehman, A. F. AU - Lieberman, J. A. AU - Dixon, L. B. PY - 2004 DA - 2004// TI - Practice guideline for the treatment of patients with schizophrenia, second edition JO - Am J Psychiatry VL - 161 UR - https://doi.org/10.1176/appi.ajp.161.1.1 DO - 10.1176/appi.ajp.161.1.1 ID - Lehman2004 ER - TY - JOUR AU - Warnez, S. AU - Alessi-Severini, S. PY - 2014 DA - 2014// TI - Clozapine: a review of clinical practice guidelines and prescribing trends JO - BMC Psychiatry VL - 14 UR - https://doi.org/10.1186/1471-244X-14-102 DO - 10.1186/1471-244X-14-102 ID - Warnez2014 ER - TY - JOUR AU - Kane, J. M. PY - 1996 DA - 1996// TI - Treatment resistant schizophrenic patients JO - J Clin Psychiatry VL - 57 ID - Kane1996 ER - TY - JOUR AU - Suzuki, T. AU - Remington, G. AU - Mulsant, B. H. PY - 2012 DA - 2012// TI - Defining treatment-resistant schizophrenia and response to antipsychotics: a review and recommendation JO - Psychiatry Res VL - 197 UR - https://doi.org/10.1016/j.psychres.2012.02.013 DO - 10.1016/j.psychres.2012.02.013 ID - Suzuki2012 ER - TY - JOUR AU - Lee, J. AU - Takeuchi, H. AU - Fervaha, G. AU - Sin, G. L. AU - Foussias, G. AU - Agid, O. PY - 2015 DA - 2015// TI - Subtyping schizophrenia by treatment response: antipsychotic development and the central role of positive symptoms JO - Can J Psychiatry VL - 60 UR - https://doi.org/10.1177/070674371506001203 DO - 10.1177/070674371506001203 ID - Lee2015 ER - TY - JOUR AU - Howes, O. D. AU - Kapur, S. PY - 2009 DA - 2009// TI - The dopamine hypothesis of schizophrenia: version III—the final common pathway JO - Schizophr Bull VL - 35 UR - https://doi.org/10.1093/schbul/sbp006 DO - 10.1093/schbul/sbp006 ID - Howes2009 ER - TY - JOUR AU - Wolkin, A. AU - Barouche, F. AU - Wolf, A. P. PY - 1989 DA - 1989// TI - Dopamine blockade and clinical response: evidence for two biological subgroups of schizophrenia JO - Am J Psychiatry VL - 146 UR - https://doi.org/10.1176/ajp.146.7.905 DO - 10.1176/ajp.146.7.905 ID - Wolkin1989 ER - TY - JOUR AU - Yilmaz, Z. AU - Zai, C. C. AU - Hwang, R. PY - 2012 DA - 2012// TI - Antipsychotics, dopamine D2 receptor occupancy and clinical improvement in schizophrenia: a meta-analysis JO - Schizophr Res VL - 140 UR - https://doi.org/10.1016/j.schres.2012.06.027 DO - 10.1016/j.schres.2012.06.027 ID - Yilmaz2012 ER - TY - JOUR AU - Stone, J. M. AU - Raffin, M. AU - Morrison, P. AU - McGuire, P. K. PY - 2009 DA - 2009// TI - The biological basis of antipsychotic response in schizophrenia JO - J Psychopharmacol VL - 24 UR - https://doi.org/10.1177/0269881109106959 DO - 10.1177/0269881109106959 ID - Stone2009 ER - TY - JOUR AU - Demjaha, A. AU - Murray, R. M. AU - McGuire, P. K. AU - Kapur, S. AU - Howes, O. PY - 2012 DA - 2012// TI - Dopamine synthesis capacity in patients with treatment-resistant schizophrenia JO - Am J Psychiatry VL - 169 UR - https://doi.org/10.1176/appi.ajp.2012.12010144 DO - 10.1176/appi.ajp.2012.12010144 ID - Demjaha2012 ER - TY - JOUR AU - Demjaha, A. AU - Egerton, A. AU - Murray, R. M. PY - 2014 DA - 2014// TI - Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function JO - Biol Psychiatry VL - 75 UR - https://doi.org/10.1016/j.biopsych.2013.06.011 DO - 10.1016/j.biopsych.2013.06.011 ID - Demjaha2014 ER - TY - JOUR AU - Egerton, A. AU - Brugger, S. AU - Raffin, M. PY - 2012 DA - 2012// TI - Anterior cingulate glutamate levels related to clinical status following treatment in first-episode schizophrenia JO - Neuropsychopharmacology VL - 37 UR - https://doi.org/10.1038/npp.2012.113 DO - 10.1038/npp.2012.113 ID - Egerton2012 ER - TY - JOUR AU - Mouchlianitis, E. AU - Bloomfield, M. A. AU - Law, V. PY - 2015 DA - 2015// TI - Treatment-resistant schizophrenia patients show elevated anterior cingulate cortex glutamate compared to treatment-responsive JO - Schizophr Bull VL - 17 ID - Mouchlianitis2015 ER - TY - JOUR AU - Juarez-Reyes, M. G. AU - Shumway, M. AU - Battle, C. AU - Bacchetti, P. AU - Hansen, M. S. AU - Hargreaves, W. A. PY - 1995 DA - 1995// TI - Restricting clozapine use: the impact of stringent eligibility criteria JO - Psychiatric Serv VL - 46 UR - https://doi.org/10.1176/ps.46.8.801 DO - 10.1176/ps.46.8.801 ID - Juarez-Reyes1995 ER - TY - JOUR AU - Essock, S. M. AU - Hargreaves, W. A. AU - Dohm, F. -. A. AU - Goethe, J. AU - Carver, L. AU - Hipshman, L. PY - 1996 DA - 1996// TI - Clozapine eligibility among state hospital patients JO - Schizophr Bull VL - 22 UR - https://doi.org/10.1093/schbul/22.1.15 DO - 10.1093/schbul/22.1.15 ID - Essock1996 ER - TY - JOUR AU - Iasevoli, F. AU - Giordano, S. AU - Balletta, R. PY - 2016 DA - 2016// TI - Treatment resistant schizophrenia is associated with the worst community functioning among severely-ill highly-disabling psychiatric conditions and is the most relevant predictor of poorer achievements in functional milestones JO - Prog Neuropsychopharmacol Biol Psychiatry VL - 65 UR - https://doi.org/10.1016/j.pnpbp.2015.08.010 DO - 10.1016/j.pnpbp.2015.08.010 ID - Iasevoli2016 ER - TY - CHAP AU - Meltzer, H. AU - Kostacoglu, A. ED - Lieberman, J. ED - Murray, R. PY - 2001 DA - 2001// TI - Treatment-resistant schizophrenia BT - Comprehensive care of schizophrenia: a textbook of clinical management PB - Martin Dunitz CY - London (UK) ID - Meltzer2001 ER - TY - JOUR AU - Kennedy, J. L. AU - Altar, C. A. AU - Taylor, D. L. AU - Degtiar, I. AU - Hornberger, J. C. PY - 2014 DA - 2014// TI - The social and economic burden of treatment-resistant schizophrenia: a systematic literature review JO - Int Clin Psychopharmacol VL - 29 UR - https://doi.org/10.1097/YIC.0b013e32836508e6 DO - 10.1097/YIC.0b013e32836508e6 ID - Kennedy2014 ER - TY - STD TI - Saragiotto BT, Yamato TP, Junior LCH, Rainbow MJ, Davis IS, Lopes AD. What are the main risk factors for running-related injuries?. Sports Med. 2014;44(8);1153–63. ID - ref26 ER - TY - JOUR AU - Goldstein, M. E. AU - Anderson, V. M. AU - Pillai, A. AU - Kydd, R. R. AU - Russell, B. R. PY - 2015 DA - 2015// TI - Glutamatergic neurometabolites in clozapine-responsive and-resistant schizophrenia JO - Int J Neuropsychopharmacol VL - 18 UR - https://doi.org/10.1093/ijnp/pyu117 DO - 10.1093/ijnp/pyu117 ID - Goldstein2015 ER - TY - JOUR AU - Anderson, V. M. AU - Goldstein, M. E. AU - Kydd, R. R. AU - Russell, B. R. PY - 2015 DA - 2015// TI - Extensive gray matter volume reduction in treatment-resistant schizophrenia JO - Int J Neuropsychopharmacol VL - 18 UR - https://doi.org/10.1093/ijnp/pyv016 DO - 10.1093/ijnp/pyv016 ID - Anderson2015 ER - TY - JOUR AU - Molina, V. AU - Reig, S. AU - Sanz, J. PY - 2008 DA - 2008// TI - Differential clinical, structural and P300 parameters in schizophrenia patients resistant to conventional neuroleptics JO - Prog Neuropsychopharmacol Biol Psychiatry VL - 32 UR - https://doi.org/10.1016/j.pnpbp.2007.08.017 DO - 10.1016/j.pnpbp.2007.08.017 ID - Molina2008 ER - TY - JOUR AU - Anttila, S. AU - Illi, A. AU - Kampman, O. AU - Mattila, K. M. AU - Lehtimaki, T. AU - Leinonen, E. PY - 2005 DA - 2005// TI - Lack of association between two polymorphisms of brain-derived neurotrophic factor and response to typical neuroleptics JO - J Neural Transm VL - 112 UR - https://doi.org/10.1007/s00702-004-0233-9 DO - 10.1007/s00702-004-0233-9 ID - Anttila2005 ER - TY - JOUR AU - Krebs, M. O. AU - Guillin, O. AU - Bourdell, M. C. PY - 2000 DA - 2000// TI - Brain derived neurotrophic factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia JO - Mol Psychiatry VL - 5 UR - https://doi.org/10.1038/sj.mp.4000749 DO - 10.1038/sj.mp.4000749 ID - Krebs2000 ER - TY - JOUR AU - Joober, R. AU - Benkelfat, C. AU - Brisebois, K. PY - 1999 DA - 1999// TI - T102C polymorphism in the 5HT2A gene and schizophrenia: relation to phenotype and drug response variability JO - J Psychiatry Neurosci VL - 24 ID - Joober1999 ER - TY - JOUR AU - Anttila, S. AU - Kampman, O. AU - Illi, A. AU - Rontu, R. AU - Lehtimaki, T. AU - Leinonen, E. PY - 2007 DA - 2007// TI - Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach JO - BMC Psychiatry VL - 7 UR - https://doi.org/10.1186/1471-244X-7-22 DO - 10.1186/1471-244X-7-22 ID - Anttila2007 ER - TY - JOUR AU - Goldberger, C. AU - Gourion, D. AU - Leroy, S. PY - 2005 DA - 2005// TI - Population-based and family-based association study of 5’UTR polymorphism of the reelin gene and schizophrenia JO - Am J Med Genet B Neuropsychiatr Genet VL - 137 UR - https://doi.org/10.1002/ajmg.b.30191 DO - 10.1002/ajmg.b.30191 ID - Goldberger2005 ER - TY - JOUR AU - Kampman, O. AU - Illi, A. AU - Hänninen, K. PY - 2006 DA - 2006// TI - RGS4 genotype is not associated with antipsychotic medication response in schizophrenia JO - J Neural Transm VL - 113 UR - https://doi.org/10.1007/s00702-006-0445-2 DO - 10.1007/s00702-006-0445-2 ID - Kampman2006 ER - TY - JOUR AU - Krebs, M. O. AU - Sautel, F. AU - Bourdel, M. C. PY - 1998 DA - 1998// TI - Dopamine D3 receptor gene variants and substance abuse in schizophrenia JO - Mol Psychiatry VL - 3 UR - https://doi.org/10.1038/sj.mp.4000411 DO - 10.1038/sj.mp.4000411 ID - Krebs1998 ER - TY - JOUR AU - Lahdelma, L. AU - Ahokas, A. AU - Andersson, L. C. AU - Huttunen, M. AU - Sarna, S. AU - Koskimies, S. PY - 1998 DA - 1998// TI - Association between HLA-A1 allele and schizophrenia gene(s) in patients refractory to conventional neuroleptics but responsive to clozapine medication JO - Tissue Antigens VL - 51 UR - https://doi.org/10.1111/j.1399-0039.1998.tb02965.x DO - 10.1111/j.1399-0039.1998.tb02965.x ID - Lahdelma1998 ER - TY - JOUR AU - Meged, S. AU - Stein, D. AU - Sitrota, P. PY - 1999 DA - 1999// TI - Human leukocyte antigen typing, response to neuroleptics and clozapine-induced agranulocytosis in Jewish Israeli schizophrenic patients JO - Int Clin Psychopharmacol VL - 14 UR - https://doi.org/10.1097/00004850-199909000-00005 DO - 10.1097/00004850-199909000-00005 ID - Meged1999 ER - TY - JOUR AU - Joober, R. AU - Rouleau, G. A. AU - Lal, S. PY - 2005 DA - 2005// TI - Increased prevalence of schizophrenia spectrum disorders in relatives of neuroleptic-nonresponsive schizophrenic patients JO - Schizophr Res VL - 77 UR - https://doi.org/10.1016/j.schres.2005.01.008 DO - 10.1016/j.schres.2005.01.008 ID - Joober2005 ER - TY - JOUR AU - Kayo, M. AU - Tassell, I. AU - Hiroce, V. AU - Menezes, A. AU - Elkis, H. PY - 2012 DA - 2012// TI - Does lack of improvement in the first two weeks predict treatment resistance in recent-onset psychosis? JO - Clinics VL - 67 UR - https://doi.org/10.6061/clinics/2012(12)20 DO - 10.6061/clinics/2012(12)20 ID - Kayo2012 ER - TY - JOUR AU - Meltzer, H. Y. AU - Rabinowitz, J. AU - Lee, M. A. PY - 1997 DA - 1997// TI - Age at onset and gender of schizophrenic patients in relation to neuroleptic resistance JO - Am J Psychiatry VL - 154 UR - https://doi.org/10.1176/ajp.154.4.475 DO - 10.1176/ajp.154.4.475 ID - Meltzer1997 ER - TY - JOUR AU - Joober, R. AU - Rouleau, G. A. AU - Lal, S. PY - 2002 DA - 2002// TI - Neuropsychological impairments in neuroleptic-responder vs. -nonresponder schizophrenic patients and healthy volunteers JO - Schizophr Res VL - 53 UR - https://doi.org/10.1016/S0920-9964(01)00279-1 DO - 10.1016/S0920-9964(01)00279-1 ID - Joober2002 ER - TY - JOUR AU - Bartolomeis, A. AU - Balletta, R. AU - Giordano, S. AU - Buonaguro, E. F. AU - Latte, G. AU - Iasevoli, F. PY - 2013 DA - 2013// TI - Differential cognitive performances between schizophrenic responders and non-responders to antipsychotics: correlation with course of the illness, psychopathology, attitude to the treatment and antipsychotics doses JO - Psychiatry Res VL - 210 UR - https://doi.org/10.1016/j.psychres.2013.06.042 DO - 10.1016/j.psychres.2013.06.042 ID - Bartolomeis2013 ER - TY - JOUR AU - Brenner, H. D. AU - Dencker, S. J. AU - Goldstein, M. J. AU - Hubbard, J. W. AU - Keegan, D. L. AU - Kruger, G. PY - 1990 DA - 1990// TI - Defining treatment refractoriness in schizophrenia JO - Schizophr Bull VL - 16 UR - https://doi.org/10.1093/schbul/16.4.551 DO - 10.1093/schbul/16.4.551 ID - Brenner1990 ER - TY - JOUR AU - Arnedo, J. AU - Svrakic, D. M. AU - Val, C. AU - Romero-Zaliz, R. AU - Hernández-Cuervo, H. AU - Fanous, A. H. PY - 2015 DA - 2015// TI - Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies JO - Am J Psychiatry VL - AiA ID - Arnedo2015 ER - TY - JOUR AU - Abi-Dargham, A. AU - Rodenhiser, J. AU - Printz, D. PY - 2000 DA - 2000// TI - Increased baseline occupancy of D2 receptors by dopamine in schizophrenia JO - PNAS USA VL - 97 UR - https://doi.org/10.1073/pnas.97.14.8104 DO - 10.1073/pnas.97.14.8104 ID - Abi-Dargham2000 ER - TY - JOUR AU - Garver, D. L. AU - Holcomb, J. A. AU - Christensen, J. D. PY - 2000 DA - 2000// TI - Heterogeneity of response to antipsychotics from multiple disorders in the schizophrenia spectrum JO - J Clin Psychiatry VL - 61 UR - https://doi.org/10.4088/JCP.v61n1213 DO - 10.4088/JCP.v61n1213 ID - Garver2000 ER - TY - JOUR AU - Mouchlianitis, E. AU - McCutcheon, R. AU - Howes, O. D. PY - 2016 DA - 2016// TI - Brain-imaging studies of treatment-resistant schizophrenia: a systematic review JO - Lancet Psychiatry VL - 31 UR - https://doi.org/10.1016/S2215-0366(15)00540-4 DO - 10.1016/S2215-0366(15)00540-4 ID - Mouchlianitis2016 ER - TY - JOUR AU - Kahn, R. S. AU - Davidson, M. AU - Siever, L. AU - Gabriel, S. AU - Apter, S. AU - Davis, K. L. PY - 1993 DA - 1993// TI - Serotonin function and treatment response to clozapine in schizophrenic patients JO - Am J Psychiatry VL - 150 UR - https://doi.org/10.1176/ajp.150.9.1337 DO - 10.1176/ajp.150.9.1337 ID - Kahn1993 ER - TY - JOUR AU - Reuter, M. AU - Hennig, J. PY - 2005 DA - 2005// TI - Pleiotropic effect of the TPH A779C polymorphism on nicotine dependence and personality JO - Am J Med Genet VL - 134 UR - https://doi.org/10.1002/ajmg.b.30153 DO - 10.1002/ajmg.b.30153 ID - Reuter2005 ER - TY - JOUR AU - Heijden, F. AU - Tuinier, S. AU - Fekkes, D. AU - Sijben, A. AU - Kahn, R. S. AU - Verhoeven, W. M. PY - 2004 DA - 2004// TI - Atypical antipsychotics and the relevance of glutamate and serotonin JO - Eur Neuropsychopharmacol VL - 14 UR - https://doi.org/10.1016/j.euroneuro.2003.09.002 DO - 10.1016/j.euroneuro.2003.09.002 ID - Heijden2004 ER - TY - JOUR AU - Mohr, P. AU - Horacek, J. AU - Motlova, L. AU - Libiger, J. AU - Czobor, P. PY - 1998 DA - 1998// TI - Prolactin response to D-fenfluramine challenge test as a predictor of treatment response to haloperidol in acute schizophrenia JO - Schizophr Res VL - 30 UR - https://doi.org/10.1016/S0920-9964(97)00124-2 DO - 10.1016/S0920-9964(97)00124-2 ID - Mohr1998 ER - TY - JOUR AU - Nakajima, S. AU - Takeuchi, H. AU - Plitman, E. AU - Fervaha, G. AU - Gerretsen, P. AU - Caravaggio, F. PY - 2015 DA - 2015// TI - Neuroimaging findings in treatment-resistant schizophrenia: a systematic review: lack of neuroimaging correlates of treatment-resistant schizophrenia JO - Schizophr Res VL - 164 UR - https://doi.org/10.1016/j.schres.2015.01.043 DO - 10.1016/j.schres.2015.01.043 ID - Nakajima2015 ER - TY - JOUR AU - López-Gil, X. AU - Babot, Z. AU - Amargós-Bosch, M. AU - Suñol, C. AU - Artigas, F. AU - Adell, A. PY - 2007 DA - 2007// TI - Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat JO - Neuropsychopharmacology VL - 32 UR - https://doi.org/10.1038/sj.npp.1301356 DO - 10.1038/sj.npp.1301356 ID - López-Gil2007 ER - TY - JOUR AU - Amitai, N. AU - Kuczenski, R. AU - Behrens, M. M. AU - Markou, A. PY - 2012 DA - 2012// TI - Repeated phencyclidine administration alters glutamate release and decreases GABA markers in the prefrontal cortex of rats JO - Neuropharmacology VL - 62 UR - https://doi.org/10.1016/j.neuropharm.2011.01.008 DO - 10.1016/j.neuropharm.2011.01.008 ID - Amitai2012 ER - TY - JOUR AU - Haukvik, U. K. AU - Hartberg, C. B. AU - Agartz, I. PY - 2013 DA - 2013// TI - Schizophrenia--what does structural MRI show? JO - Tidsskr Nor Laegeforen VL - 133 UR - https://doi.org/10.4045/tidsskr.12.1084 DO - 10.4045/tidsskr.12.1084 ID - Haukvik2013 ER - TY - JOUR AU - Shepherd, A. M. AU - Laurens, K. R. AU - Matheson, S. L. AU - Carr, V. J. AU - Green, M. J. PY - 2012 DA - 2012// TI - Systematic meta-review and quality assessment of the structural brain alterations in schizophrenia JO - Neurosci Biobehav Rev VL - 36 UR - https://doi.org/10.1016/j.neubiorev.2011.12.015 DO - 10.1016/j.neubiorev.2011.12.015 ID - Shepherd2012 ER - TY - JOUR AU - Garcia, G. J. AU - Chagas, M. H. AU - Silva, C. H. AU - Machado-de-Sousa, J. P. AU - Crippa, J. A. AU - Hallak, J. E. PY - 2015 DA - 2015// TI - Structural and functional neuroimaging findings associated with the use of clozapine in schizophrenia: a systematic review JO - Rev Bras Psiquiatr VL - 37 UR - https://doi.org/10.1590/1516-4446-2014-1387 DO - 10.1590/1516-4446-2014-1387 ID - Garcia2015 ER - TY - JOUR AU - Zipursky, R. B. AU - Zhang-Wong, J. AU - Lambe, E. K. AU - Bean, G. AU - Beiser, M. PY - 1998 DA - 1998// TI - MRI correlates of treatment response in first episode psychosis JO - Schizophr Res VL - 30 UR - https://doi.org/10.1016/S0920-9964(97)00126-6 DO - 10.1016/S0920-9964(97)00126-6 ID - Zipursky1998 ER - TY - JOUR AU - Szeszko, P. R. AU - Narr, K. L. AU - Phillips, O. R. PY - 2010 DA - 2010// TI - Magnetic resonance imaging predictors of treatment response in first-episode schizophrenia JO - Schizophr Bull VL - 38 UR - https://doi.org/10.1093/schbul/sbq126 DO - 10.1093/schbul/sbq126 ID - Szeszko2010 ER - TY - JOUR AU - Molina, V. AU - Reig, S. AU - Sanz, J. PY - 2005 DA - 2005// TI - Increase in gray matter and decrease in white matter volumes in the cortex during treatment with atypical neuroleptics in schizophrenia JO - Schizophr Res VL - 80 UR - https://doi.org/10.1016/j.schres.2005.07.031 DO - 10.1016/j.schres.2005.07.031 ID - Molina2005 ER - TY - JOUR AU - Hawi, Z. AU - Straub, R. E. AU - O’Neill, A. AU - Kendler, K. S. AU - Walsh, D. AU - Gill, M. PY - 1998 DA - 1998// TI - No linkage or linkage disequilibrium between brain-derived neurotrophic factor (BDNF) dinucleotide repeat polymorphism and schizophrenia in Irish families JO - Psychiatry Res VL - 81 UR - https://doi.org/10.1016/S0165-1781(98)00076-6 DO - 10.1016/S0165-1781(98)00076-6 ID - Hawi1998 ER - TY - JOUR AU - Zhang, J. P. AU - Lencz, T. AU - Geisler, S. AU - DeRosse, P. AU - Bromet, E. J. AU - Malhotra, A. K. PY - 2013 DA - 2013// TI - Genetic variation in BDNF is associated with antipsychotic treatment resistance in patients with schizophrenia JO - Schizophr Res VL - 146 UR - https://doi.org/10.1016/j.schres.2013.01.020 DO - 10.1016/j.schres.2013.01.020 ID - Zhang2013 ER - TY - JOUR AU - Zai, G. AU - Zai, C. C. AU - Chowdhury, N. I. PY - 2012 DA - 2012// TI - The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain JO - Prog Neuropsychopharmacol Biol Psychiatry VL - 39 UR - https://doi.org/10.1016/j.pnpbp.2012.05.014 DO - 10.1016/j.pnpbp.2012.05.014 ID - Zai2012 ER - TY - JOUR AU - Akahane, A. AU - Kunugi, H. AU - Tanaka, H. AU - Nanko, S. PY - 2002 DA - 2002// TI - Association analysis of polymorphic CGG repeat in 5’ UTR of the reelin and VLDLR genes with schizophrenia JO - Schizophr Res VL - 58 UR - https://doi.org/10.1016/S0920-9964(01)00398-X DO - 10.1016/S0920-9964(01)00398-X ID - Akahane2002 ER - TY - JOUR AU - Folsom, T. D. AU - Fatemi, S. H. PY - 2013 DA - 2013// TI - The involvement of Reelin in neurodevelopmental disorders JO - Neuropharmacology VL - 68 UR - https://doi.org/10.1016/j.neuropharm.2012.08.015 DO - 10.1016/j.neuropharm.2012.08.015 ID - Folsom2013 ER - TY - JOUR AU - Silverman, J. M. AU - Mohs, R. C. AU - Davidson, M. PY - 1987 DA - 1987// TI - Familial schizophrenia and treatment response JO - Am J Psychiatry VL - 144 UR - https://doi.org/10.1176/ajp.144.10.1271 DO - 10.1176/ajp.144.10.1271 ID - Silverman1987 ER - TY - JOUR AU - Frank, J. AU - Lang, M. AU - Witt, S. H. PY - 2015 DA - 2015// TI - Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients JO - Mol Psychiatry VL - 20 UR - https://doi.org/10.1038/mp.2014.56 DO - 10.1038/mp.2014.56 ID - Frank2015 ER - TY - JOUR AU - Martin, A. K. AU - Mowry, B. PY - 2016 DA - 2016// TI - Increased rare duplication burden genomewide in patients with treatment-resistant schizophrenia JO - Psychol Med VL - 46 UR - https://doi.org/10.1017/S0033291715001701 DO - 10.1017/S0033291715001701 ID - Martin2016 ER - TY - JOUR AU - Maes, M. AU - Bocchio Chiavetto, L. AU - Bignotti, S. PY - 2002 DA - 2002// TI - Increased serum interleukin-8 and interleukin-10 in schizophrenic patients resistant to treatment with neuroleptics and the stimulatory effects of clozapine on serum leukemia inhibitory factor receptor JO - Schizophr Res VL - 54 UR - https://doi.org/10.1016/S0920-9964(00)00094-3 DO - 10.1016/S0920-9964(00)00094-3 ID - Maes2002 ER - TY - JOUR AU - Lin, A. AU - Kenis, G. AU - Bignotti, S. PY - 1998 DA - 1998// TI - The inflammatory response system in treatment-resistant schizophrenia: increased serum interleukin-6 JO - Schizophr Res VL - 32 UR - https://doi.org/10.1016/S0920-9964(98)00034-6 DO - 10.1016/S0920-9964(98)00034-6 ID - Lin1998 ER - TY - JOUR AU - Liou, Y. J. AU - Wang, H. H. AU - Lee, M. T. PY - 2012 DA - 2012// TI - Genome-wide association study of treatment refractory schizophrenia in Han Chinese JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0033598 DO - 10.1371/journal.pone.0033598 ID - Liou2012 ER - TY - JOUR AU - Drago, A. AU - Giegling, I. AU - Schäfer, M. PY - 2014 DA - 2014// TI - Genome-wide association study supports the role of the immunological system and of the neurodevelopmental processes in response to haloperidol treatment JO - Pharmacogenet Genomics VL - 24 UR - https://doi.org/10.1097/FPC.0000000000000052 DO - 10.1097/FPC.0000000000000052 ID - Drago2014 ER - TY - JOUR AU - Tsuang, M. T. PY - 1982 DA - 1982// TI - Memory deficit and long-term outcome in schizophrenia: a preliminary study JO - Psychiatry Res VL - 6 UR - https://doi.org/10.1016/0165-1781(82)90025-7 DO - 10.1016/0165-1781(82)90025-7 ID - Tsuang1982 ER - TY - JOUR AU - Carbon, M. AU - Correll, C. U. PY - 2014 DA - 2014// TI - Clinical predictors of therapeutic response to antipsychotics in schizophrenia JO - Dialogues Clin Neurosci VL - 16 ID - Carbon2014 ER - TY - JOUR AU - Samara, M. T. AU - Leucht, C. AU - Leeflang, M. M. AU - Anghelescu, I. G. AU - Chung, Y. C. AU - Crespo-Facorro, B. PY - 2015 DA - 2015// TI - Early improvement as a predictor of later response to antipsychotics in schizophrenia: a diagnostic test review JO - Am J Psychiatry VL - 172 UR - https://doi.org/10.1176/appi.ajp.2015.14101329 DO - 10.1176/appi.ajp.2015.14101329 ID - Samara2015 ER - TY - JOUR AU - Hollis, C. PY - 2000 DA - 2000// TI - Adult outcomes of child-and adolescent-onset schizophrenia: diagnostic stability and predictive validity JO - Am J Psychiatry VL - 157 UR - https://doi.org/10.1176/appi.ajp.157.10.1652 DO - 10.1176/appi.ajp.157.10.1652 ID - Hollis2000 ER - TY - JOUR AU - Kessler, R. C. AU - Amminger, G. P. AU - Aguilar‐Gaxiola, S. AU - Alonso, J. AU - Lee, S. AU - Ustun, T. B. PY - 2007 DA - 2007// TI - Age of onset of mental disorders: a review of recent literature JO - Curr Opin Psychiatry VL - 20 UR - https://doi.org/10.1097/YCO.0b013e32816ebc8c DO - 10.1097/YCO.0b013e32816ebc8c ID - Kessler2007 ER - TY - JOUR AU - Teo, C. AU - Borlido, C. AU - Kennedy, J. L. AU - Luca, V. PY - 2013 DA - 2013// TI - The role of ethnicity in treatment refractory schizophrenia JO - Compr Psychiatry VL - 54 UR - https://doi.org/10.1016/j.comppsych.2012.07.002 DO - 10.1016/j.comppsych.2012.07.002 ID - Teo2013 ER - TY - JOUR AU - Morgan, C. AU - Hutchinson, G. PY - 2010 DA - 2010// TI - The social determinants of psychosis in migrant and ethnic minority populations: a public health tragedy JO - Psychol Med VL - 40 UR - https://doi.org/10.1017/S0033291709005546 DO - 10.1017/S0033291709005546 ID - Morgan2010 ER - TY - STD TI - Wimberley T, Støvring T, Sørensen HJ, Horsdal HT, MacCabe JH, Gasse C. Predictors of Treatment Resistance in Schizophrenia: a population based cohort study. Lancet Psychiatry. 2016;3(4):358-66.  ID - ref81 ER - TY - STD TI - Howes OD, McCutcheon R, Agid O, Bartolomeis A, van Beveren NJM, Birnbaum ML et al. Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group consensus guidelines on diagnosis and terminology. Am J Psychiatry. 2016 (in press). ID - ref82 ER - TY - JOUR AU - Andreasen, N. C. AU - Carpenter, W. T. AU - Kane, J. M. AU - Lasser, R. A. AU - Marder, S. R. AU - Weinberger, D. R. PY - 2005 DA - 2005// TI - Remission in schizophrenia: proposed criteria and rationale for consensus JO - Am J Psychiatry VL - 162 UR - https://doi.org/10.1176/appi.ajp.162.3.441 DO - 10.1176/appi.ajp.162.3.441 ID - Andreasen2005 ER - TY - JOUR AU - Sarpal, D. K. AU - Argyelan, M. AU - Robinson, D. G. PY - 2016 DA - 2016// TI - Baseline striatal functional connectivity as a predictor of response to antipsychotic drug treatment JO - Am J Psychiatry VL - 173 UR - https://doi.org/10.1176/appi.ajp.2015.14121571 DO - 10.1176/appi.ajp.2015.14121571 ID - Sarpal2016 ER -