Table 2 Study components for which specific consent was requested, instruments and details about the method, number of items or time to complete

 Diagnostic interview and clinical data

Structured Clinical Interview for DSM-IV Axis I Disorders- Clinical Version [21] or

Mini-International Neuropsychiatric Interview [22, 23] from medical records

30–60 min

 Clinical examination

Height, weight, waist-hip measurement, blood pressure, pulse.

15 min

 Blood

EDTA-blood and serum 25 ml

Conducted at the clinic

 Saliva

6 samples over 1 day

Conducted at home

 Feces sampling

1 ml sample

Conducted at home

 Lumbar fluid^b

10 ml

Conducted at clinic

 Adrenal function test^b

Dexametasone test

Conducted at home

 Alcohol and drug use

Alcohol Use Disorders Identification Test and Drug Use Disorders Identification Test [24]

21 items

 Depressive symptoms

Montgomery Åsberg Depression Rating Scale [25–27]

9 items

 Personality

Swedish universities Scales of Personality [28]

91 items

 Disability

The Sheehan Disability Scale [29, 30]

5 items

 Self harm

Deliberate Self Harm Inventory: 9-Item Version [31]

9 items

 Sleep quality

Pittsburgh Sleep Quality Index [32]

19 items

 Traumatic life events

Early Trauma Inventory [33]

62 items

 Sociodemografics, medical history, heredity, menstruation patterns in women, pain

Questions identical to those used in LifeGene (http://www.lifegene.se) and EpiHealth (http://www.epihealth.se)

30 items

 Gastrointestinal symptoms

The Gastrointestinal Symptom Rating Scale [34]

15 items

 Participant reactions

Response to Research Participation Questionnaire [13, 35]

12 items

 National registers^b

Registers concerning cause of death, disease, pharmaceutical usage

 Re-contact^b

Permission to contact follow-up.