Skip to main content

Table 4 Comparison of pharmacotherapy among depressed eating disorder patients with or without lifetime hypomania/mania episode at enrollment

From: Comparison of associated features and drug treatment between co-occurring unipolar and bipolar disorders in depressed eating disorder patients

Variables Eating disorders with MDD Eating disorders with bipolar II disorder Eating disorders with bipolar I disorder 2 vs. 1 3 vs. 1 3 vs. 2
(1) (2) (3)
(n = 133) (n = 55) (n = 39)
N (%) N (%) N (%) AOR (95% CI) AOR (95% CI) AOR (95% CI)
Antidepressant monotherapy 61 (48.0) 31 (56.4) 10 (27.0) 1.23 (0.62, 2.42) 0.35 (0.15, 0.83) 0.28 (0.11, 0.72)
mood stabilizer monotherapy 0 1 (1.8) 0 NA NA NA
Atypical antipsychotic monotherapy 32 (25.2) 6 (10.9) 9 (24.3) 0.41 (0.15, 1.09) 1.04 (0.41, 2.61) 2.65 (0.82, 8.59)
Antidepressant plus mood stabilizers 1 (0.8) 0 1 (2.7) NA NA NA
Antidepressant plus antipsychotic 17 (13.4) 10 (18.2) 9 (24.3) 1.44 (0.56, 3.47) 2.09 (0.81, 5.37) 1.36 (0.46, 4.03)
Antidepressant plus mood stabilizers and antipsychotics 1 (0.8) 1 (1.8) 1 (2.7) 2.26 (0.13, 39.12) 4.00 (0.23, 68.78) 1.78 (0.10, 30.80)
Any antidepressant 80 (63.0) 42 (76.4) 21 (56.8) 1.70 (0.78, 3.72) 0.70 (0.31, 1.60) 0.38 (0.15, 0.99)
Any mood stabilizer 5 (3.9) 3 (5.5) 6 (16.2) 1.01 (0.25, 4.88) 3.95 (1.06, 14.71) 3.96 (0.90, 17.44)
Any atypical antipsychotic 51 (40.2) 17 (30.9) 21 (56.8) 0.72 (0.36, 1.47) 2.13 (0.97, 4.65) 2.92 (1.18, 7.20)
  1. MDD major depressive disorder
  2. Data mission for 6 and 2 persons in eating disorders with MDD and eating disorders with bipolar I disorder, respectively
  3. AOR: odd ratio adjusted for age, gender, and eating disorder subtypes
  4. Values in bold type indicated statistically significant