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Table 3 Linear mixed model analyses

From: Effects of five-minute internet-based cognitive behavioral therapy and simplified emotion-focused mindfulness on depressive symptoms: a randomized controlled trial

   Predicted means (95% CI) Intervention effect (95% CI), p value
  Time iCBT sEFM Waiting list iCBT – waiting list sEFM – waiting list iCBT – sEFM
CES-D T0 24.66 (23.98, 25.35) 24.56 (23.88, 25.25) 24.47 (23.79, 25.16)    
T1 22.87 (22.10, 23.64) 23.34 (22.56, 24.11) 23.96 (23.22, 24.71) −1.28 (−2.58, 0.02); 0.05 −0.72 (−2.02, 0.59); 0.28 −0.56 (−1.88, 0.76); 0.41
T2 23.14 (22.35, 23.94) 23.88 (23.08, 24.67) 23.49 (22.73, 24.25) −0.53 (−1.86, 0.80); 0.43 0.30 (−1.03, 1.63); 0.66 –0.83 (−2.18, 0.52); 0.23
T3 22.07 (21.22, 22.93) 23.52 (22.65, 24.38)     −1.56 (−2.94, –0.18); 0.03
PHQ-9 T0 9.74 (9.36, 10.11) 9.71 (9.33, 10.09) 9.72 (9.34, 10.10)    
T1 9.00 (8.57, 9.42) 8.68 (8.25, 9.11) 9.66 (9.25, 10.07) −0.68 (−1.42, 0.05); 0.07 −0.97 (−1.70, −0.23); 0.01 0.29 (−0.46, 1.03); 0.45
T2 9.52 (9.08, 9.96) 9.25 (8.81, 9.69) 9.50 (9.08, 9.92) 0.00 (−0.74, 0.75); 0.99 −0.24 (−0.99, 0.51); 0.53 0.24 (−0.52, 1.00); 0.53
T3 8.94 (8.47, 9.41) 9.24 (8.76, 9.72)     −0.34 (−1.12, 0.44); 0.40
GAD-7 T0 7.09 (6.75, 7.43) 7.09 (6.75, 7.42) 7.04 (6.70, 7.38)    
T1 6.38 (6.00, 6.77) 6.54 (6.16, 6.93) 6.79 (6.42, 7.15) −0.45 (−1.10, 0.20); 0.18 −0.29 (–0.94, 0.37); 0.39 −0.16 (−0.83, 0.50); 0.63
T2 7.01 (6.62, 7.40) 7.03 (6.64, 7.42) 6.84 (6.46, 7.22) 0.12 (−0.54, 0.79); 0.72 0.14 (−0.53, 0.81); 0.68 −0.02 (−0.69, 0.66); 0.96
T3 6.45 (6.03, 6.87) 7.17 (6.75, 7.59)     −0.72 (−1.41, −0.04); 0.04
  1. iCBT internet-based cognitive behavioral therapy, sEFM simplified emotion-focused mindfulness. CI confidence interval. T0 = baseline, T1 = postintervention, T2 = six weeks after T1, T3 = six weeks after T2. CES-D the Center for Epidemiological Studies Depression scale, PHQ-9 the Patient Health Questionnaire-9, GAD-7 the Generalized Anxiety Disorder-7. For T0 through T2, predicted means (95% CI) from mixed model with outcome measure at baseline, time (T0, T1, T2), treatment (iCBT, sEFM, Waiting list), and interaction between time and treatment as fixed effects. For T3, predicted means (95% CI) from mixed model with outcome measure at baseline, time (T0, T1, T2, T3), treatment (iCBT, sEFM, delayed iCBT, delayed sEFM), and interaction between time and treatment as fixed effects. Fixed effect of time × treatment interaction as an indicator of intervention effect. Values in bold are significant at 5%