Table 3 Changes in the prevalence of the use of specific psychotropic drug groups among adults aged 60-79 years in Germany. National Health Interview and Examination Surveys GNHIES98 (1997–99) and DEGS1 (2008–11)

1. All anti-depressants (St. John’s wort and all synthetical antidepressants)

96

6.4

5.2

7.9

173

7.9

6.5

9.5

1.4

-0.6

3.4

.157

1.7

-1.8

5.2

0.343

 1.1 St. John’s wort (N06AP)

47

2.9

2.1

3.9

27

1.1

0.8

1.7

-1.7

-2.7

-0.8

<.001

-5.0

-7.9

-2.0

0.001

 1.2 All synthetical antidepressants

54

3.9

2.9

5.2

151

6.9

5.5

8.5

3.0

1.2

4.8

.001

6.0

2.5

9.4

0.001

  1.2.1. NSMRIs^c (N06AA)

45

3.6

2.6

4.8

80

3.8

2.8

5.2

0.3

-1.3

1.8

.741

0.4

-2.7

3.5

0.806

  1.2.2. SSRIs^d (N06AB)

3

0.3

0.1

1.0

47

2.0

1.4

2.7

1.7

1.0

2.4

.001

4.1

2.4

5.8

<.0001

2. All hypnotics & sedatives (synth., antihistamines and phytoceuticals)

62

3.6

2.8

4.8

98

3.3

2.6

4.3

-0.3

-1.6

1.0

.644

-1.3

-3.5

0.9

0.234

 2.1 All synth. (N05C) and antihistamines (N05CM)

31

1.6

1.1

2.4

52

1.6

1.1

2.2

0.0

-0.9

0.8

.921

-0.1

-1.7

1.4

0.861

  2.1.1. Hypnotics & sedatives (N05C)

31

1.6

1.1

2.4

42

1.3

0.9

1.9

-0.3

-1.1

0.5

.430

-0.6

-2.2

0.9

0.412

 2.2. All phytoceuticals

32

2.1

1.4

3.0

51

1.9

1.3

2.6

-0.2

-1.2

0.8

.703

-0.6

-1.9

0.6

0.307

  2.2.1. Valerian (N05CP)

28

1.8

1.2

2.7

42

1.5

1.0

2.1

-0.3

-1.2

0.6

.453

-0.5

-1.7

0.7

0.408

3. Benzodiazepines and benzodiazepine-related drugs

64

3.9

2.9

5.2

84

3.3

2.4

4.4

-0.6

-2.1

0.8

.389

-2.0

-5.0

0.9

0.176

 3.1. Benzodiazepines (N05BA, N05CD, N03AE01)

57

3.7

2.8

5.0

57

2.5

1.8

3.5

-1.2

-2.6

0.2

.081

-3.4

-6.3

-0.4

0.024

 3.2. Benzodiazepine-related drugs (Z-drugs) (N05CF)

8

0.2

0.1

0.5

28

0.8

0.5

1.3

0.6

0.2

1.0

.003

1.3

0.6

2.1

<0.001

4. All anti-dementia drugs incl. ginkgo biloba

34

2.2

1.4

3.4

97

4.2

3.3

5.4

2.0

0.7

3.3

.005

3.2

1.3

5.1

0.001

 4.1. Ginkgo biloba (N06DP01)

34

2.2

1.4

3.4

88

3.8

2.9

4.8

1.6

0.3

2.8

.022

2.4

1.0

3.8

0.001

5. Narcotic analgesics (N02A)

39

3.0

2.1

4.2

96

4.1

3.2

5.3

1.2

-0.3

2.6

.121

3.9

0.5

7.3

0.026

6. Anti-epileptics (N03)

14

1.0

0.5

1.7

63

2.3

1.7

3.3

1.4

0.4

2.3

.008

3.6

1.7

5.5

<0.001

7. Antiparkinson drugs (N04)

19

1.1

.7

1.8

32

1.2

0.7

2.0

0.1

-0.7

0.9

.806

-0.1

-1.4

1.3

0.934

8. Anxiolytics (N05B)

34

2.4

1.6

3.5

48

2.2

1.5

3.1

-0.2

-1.4

1.0

.751

-1.2

-3.2

0.9

0.268