Deficits of perceived spatial separation induced prepulse inhibition in patients with schizophrenia: relationships to symptoms and neurocognition

Table 2 Between-group differences in modified PPI

Variable	HC	SZ	t	p ^a	Cohen’s d
Variable	N = 50	N = 75	t	p ^a	Cohen’s d
Startle
Mean (±SD)	50.4 ± 21.3	45.4 ± 24.0	1.18	0.24	0.22
Median (range)	47.5(14.7-81.9)	42.9(8.2-111.7)
Habituation
Mean (±SD)	14.9 ± 31.0	15.9 ± 22.0	0.24	0.84	0.04
Median (range)	15.8(−13.2-44.7)	16.6(−20.6-52.4)
PSC-PPI
Mean (±SD)	31.7 ± 25.6	9.4 ± 29.3	4.38	0.00	0.84
Median (range)	36.2(−32.7-77.8)	12.9(−5.9-70.8)
PSS-PPI
Mean (±SD)	50.7 ± 29.4	13.0 ± 29.8	6.97	0.00	1.27
Median (range)	48.6(−6.3-91.1)	17.29(−69.6-73.5)

Note: Data are expressed as mean ± SD, SD standard deviation, SZ schizophrenia patients, HC healthy controls, PPI prepulse inhibition, PSC-PPI perceived spatial co-location PPI, PSS-PPI perceived spatial separation PPI; ^a indicates p value for independent sample t-test

ISSN: 1471-244X