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Table 4 Association between cardiac function parameters and pharmacological class of antipsychotics

From: Clinicians’ adherence to clinical practice guidelines for cardiac function monitoring during antipsychotic treatment: a retrospective report on 434 patients with severe mental illness

 

Pharmacological class of antipsychotics

  

Monitoring parameters

First generation

Second generation

χ 2

P-value

Presence of ECG testing before AP treatment

80 (21.5)

200 (20.5)

0.2

0.7

Presence of ECG testing during AP treatment

101 (27.2)

336 (34.4)

6.5

0.01

Presence of electrolytes levels before AP treatment

81 (21.8)

214 (21.9)

0.004

1

Presence of electrolytes levels during AP treatment

100 (26.9)

327 (33.5)

5.5

0.02

Presence of personal history of pre-existing cardiac disease

26 (7.0)

40 (4.1)

4.8

0.03

Number of cardiac function parameters tested

 0

165 (44.4)

437 (44.8)

11.4a

0.04a

 1

70 (18.8)

152 (15.6)

 2

108 (29.0)

258 (26.4)

 3

14 (3.8)

71 (7.3)

 4

15 (4.0)

50 (5.1)

 5

0 (0.0)

8 (0.8)

  1. AP antipsychotic
  2. ECG electrocardiogram
  3. a χ 21000 sample bootstrap