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Table 4 Association between cardiac function parameters and pharmacological class of antipsychotics

From: Clinicians’ adherence to clinical practice guidelines for cardiac function monitoring during antipsychotic treatment: a retrospective report on 434 patients with severe mental illness

  Pharmacological class of antipsychotics   
Monitoring parameters First generation Second generation χ 2 P-value
Presence of ECG testing before AP treatment 80 (21.5) 200 (20.5) 0.2 0.7
Presence of ECG testing during AP treatment 101 (27.2) 336 (34.4) 6.5 0.01
Presence of electrolytes levels before AP treatment 81 (21.8) 214 (21.9) 0.004 1
Presence of electrolytes levels during AP treatment 100 (26.9) 327 (33.5) 5.5 0.02
Presence of personal history of pre-existing cardiac disease 26 (7.0) 40 (4.1) 4.8 0.03
Number of cardiac function parameters tested
 0 165 (44.4) 437 (44.8) 11.4a 0.04a
 1 70 (18.8) 152 (15.6)
 2 108 (29.0) 258 (26.4)
 3 14 (3.8) 71 (7.3)
 4 15 (4.0) 50 (5.1)
 5 0 (0.0) 8 (0.8)
  1. AP antipsychotic
  2. ECG electrocardiogram
  3. a χ 21000 sample bootstrap