Clinicians’ adherence to clinical practice guidelines for cardiac function monitoring during antipsychotic treatment: a retrospective report on 434 patients with severe mental illness

Table 6 Association between individual risk factors for QT-related arrhythmias and TdP, and pharmacological class of antipsychotics

	Pharmacological class of antipsychotics
Factor	First generation	Second generation	χ ²	P-value
Presence of comorbid somatic illnesses	191 (51.3)	476 (48.8)	0.7	0.4
Presence of cardiac comorbidities	17 (4.6)	34 (3.5)	0.9	0.35
Presence of vascular comorbidities	37 (9.9)	107 (11.0)	0.3	0.6
Use of pharmacological treatments determining QT prolongation during AP therapy	316 (84.9)	744 (76.3)	11.9	0.001

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