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Table 3 Sensitivity and specificity for PTSD diagnosis across various cut-off scores of PCL-C

From: Validity of the posttraumatic stress disorders (PTSD) checklist in pregnant women

Cut-off Score

Sensitivity (95% CI)

Specificity (95% CI)

Youden index

+PV (95% CI)

-PV (95% CI)

+LR (95% CI)

-LR (95% CI)

PR

20

0.95 (0.90, 0.99)

0.23 (0.22, 0.25)

0.18

0.04 (0.03, 0.05)

0.99 (0.98, 1.00)

1.24 (1.19, 1.30)

0.20 (0.08, 0.47)

0.77

22

0.91 (0.84, 0.96)

0.41 (0.39, 0.43)

0.32

0.05 (0.04, 0.06)

0.99 (0.99, 1.00)

1.53 (1.44, 1.64)

0.22 (0.12, 0.41)

0.60

24

0.86 (0.78, 0.92)

0.54 (0.52, 0.55)

0.40

0.06 (0.05, 0.07)

0.99 (0.99, 1.00)

1.86 (1.70, 2.02)

0.26 (0.16, 0.42)

0.48

26

0.86 (0.78, 0.92)

0.63 (0.62, 0.65)

0.49

0.08 (0.06, 0.09)

0.99 (0.99, 1.00)

2.35 (2.16, 2.57)

0.22 (0.14, 0.35)

0.38

28

0.68 (0.58, 0.77)

0.70 (0.69, 0.72)

0.38

0.07 (0.06, 0.09)

0.99 (0.98, 0.99)

2.29 (1.99, 2.64)

0.46 (0.35, 0.60)

0.31

30

0.49 (0.39, 0.59)

0.76 (0.74, 0.77)

0.25

0.06 (0.05, 0.08)

0.98 (0.97, 0.98)

2.01 (1.64, 2.46)

0.67 (0.56, 0.81)

0.25

35

0.40 (0.31, 0.50)

0.87 (0.86, 0.88)

0.27

0.09 (0.07, 0.12)

0.98 (0.97, 0.98)

3.01 (2.35, 3.84)

0.69 (0.59, 0.81)

0.14

40

0.26 (0.18, 0.36)

0.91 (0.90, 0.92)

0.17

0.10 (0.06, 0.13)

0.97 (0.97, 0.98)

3.05 (2.19, 4.25)

0.81 (0.72, 0.90)

0.09

45

0.13 (0.07, 0.21)

0.95 (0.94, 0.95)

0.08

0.08 (0.04, 0.12)

0.97 (0.96, 0.98)

2.46 (1.48, 4.09)

0.92 (0.85, 0.99)

0.06

  1. Abbreviations: +PV positive predicted value, −PV negative predicted value, +LR positive likelihood ratio, −LR negative likelihood ratio, PR prevalence; Bold text indicates the optimum cut-off