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Table 3 Sensitivity and specificity for PTSD diagnosis across various cut-off scores of PCL-C

From: Validity of the posttraumatic stress disorders (PTSD) checklist in pregnant women

Cut-off Score Sensitivity (95% CI) Specificity (95% CI) Youden index +PV (95% CI) -PV (95% CI) +LR (95% CI) -LR (95% CI) PR
20 0.95 (0.90, 0.99) 0.23 (0.22, 0.25) 0.18 0.04 (0.03, 0.05) 0.99 (0.98, 1.00) 1.24 (1.19, 1.30) 0.20 (0.08, 0.47) 0.77
22 0.91 (0.84, 0.96) 0.41 (0.39, 0.43) 0.32 0.05 (0.04, 0.06) 0.99 (0.99, 1.00) 1.53 (1.44, 1.64) 0.22 (0.12, 0.41) 0.60
24 0.86 (0.78, 0.92) 0.54 (0.52, 0.55) 0.40 0.06 (0.05, 0.07) 0.99 (0.99, 1.00) 1.86 (1.70, 2.02) 0.26 (0.16, 0.42) 0.48
26 0.86 (0.78, 0.92) 0.63 (0.62, 0.65) 0.49 0.08 (0.06, 0.09) 0.99 (0.99, 1.00) 2.35 (2.16, 2.57) 0.22 (0.14, 0.35) 0.38
28 0.68 (0.58, 0.77) 0.70 (0.69, 0.72) 0.38 0.07 (0.06, 0.09) 0.99 (0.98, 0.99) 2.29 (1.99, 2.64) 0.46 (0.35, 0.60) 0.31
30 0.49 (0.39, 0.59) 0.76 (0.74, 0.77) 0.25 0.06 (0.05, 0.08) 0.98 (0.97, 0.98) 2.01 (1.64, 2.46) 0.67 (0.56, 0.81) 0.25
35 0.40 (0.31, 0.50) 0.87 (0.86, 0.88) 0.27 0.09 (0.07, 0.12) 0.98 (0.97, 0.98) 3.01 (2.35, 3.84) 0.69 (0.59, 0.81) 0.14
40 0.26 (0.18, 0.36) 0.91 (0.90, 0.92) 0.17 0.10 (0.06, 0.13) 0.97 (0.97, 0.98) 3.05 (2.19, 4.25) 0.81 (0.72, 0.90) 0.09
45 0.13 (0.07, 0.21) 0.95 (0.94, 0.95) 0.08 0.08 (0.04, 0.12) 0.97 (0.96, 0.98) 2.46 (1.48, 4.09) 0.92 (0.85, 0.99) 0.06
  1. Abbreviations: +PV positive predicted value, −PV negative predicted value, +LR positive likelihood ratio, −LR negative likelihood ratio, PR prevalence; Bold text indicates the optimum cut-off