Table 1 Well-characterized onconeural antibodies and their associated tumors and syndromes (Modified after [7])
Onconeural antibody | Tumorsa | CNS syndromesa |
|---|---|---|
Hu (ANNA-1) | SCLC, other lung ca., prostate ca. | PCD, LE, PEM, OMS, BE, myelitis |
Ri (ANNA-2) | Mamma ca., SCLC, other lung ca. | BE, OMS, PCD, LE, PEM, myelitis |
Yo (PCA-1) | Ovary ca., uterus ca., mamma ca. | PCD |
CRMP-5 (CV2) | SCLC, other lung ca., thymoma | PCD, LE, PEM, BE, myelitis |
Ma1 | Lung ca., mamma ca., colon ca. | BE, PCD, PEM, LE, OMS |
Ma2 (Ta) | Testis ca. | LE, PCD, Dienc. and brainstem symptoms |
Amphiphysin | Mamma ca., SCLC, colon ca. | SPS, PEM, PCD, LE |
Recoverin | SCLC, other lung ca.,mamma ca. | Retinopathy |
Tr | Lymphoma | PCD |
SOX1 | SCLC | LE, PCD, BE |