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Table 3 Tmax and T1/2 (mean (SD)) of aripiprazole after administration of long acting injectable aripiprazole (Abilify Maintena®) and aripiprazole lauroxil (Aristada®)

From: Pharmacogenetic evaluation to assess breakthrough psychosis with aripiprazole long-acting injection: a case report

 

After single gluteal injection of aripiprazole 400 mg equivalents

After 4th gluteal injection of aripiprazole 300 mg equivalentsa

Aripiprazole LAI

Aripiprazole lauroxil

Aripiprazole LAI

Aripiprazole lauroxil

Tmax (day)

22 (4–22)b

44.0 (11.7)

6.5 (0.5–21.2)b

21.1

T1/2 (day)

10.5 (3.9)

18.0 (4.8)

29.9 (8.0)

29 (6)

  1. aPharmacokinetic parameters at steady-state. Data for the 400 mg equivalents is not available for aripiprazole lauroxil. For the purpose of comparison between two agents, data for the 300 mg equivalents is included
  2. bReported as median (range)