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Association of schizophrenia onset age and white matter integrity with treatment effect of D-cycloserine: a randomized placebo-controlled double-blind crossover study

  • Kazuo Takiguchi1, 2,
  • Akihito Uezato1,
  • Michio Itasaka1,
  • Hidenori Atsuta1,
  • Kenji Narushima1,
  • Naoki Yamamoto1, 3,
  • Akeo Kurumaji1,
  • Makoto Tomita4,
  • Kazunari Oshima1, 5,
  • Kosaku Shoda5,
  • Mai Tamaru6,
  • Masahito Nakataki6,
  • Mitsutoshi Okazaki7,
  • Sayuri Ishiwata1,
  • Yasuyoshi Ishiwata8,
  • Masato Yasuhara8,
  • Kunimasa Arima7,
  • Tetsuro Ohmori6 and
  • Toru Nishikawa1Email author
Contributed equally
BMC PsychiatryBMC series – open, inclusive and trusted201717:249

https://doi.org/10.1186/s12888-017-1410-3

Received: 29 July 2016

Accepted: 29 June 2017

Published: 12 July 2017

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
29 Jul 2016 Submitted Original manuscript
28 Oct 2016 Reviewed Reviewer Report - Sarah Wijtenburg
26 Feb 2017 Reviewed Reviewer Report - René Mandl
24 Apr 2017 Author responded Author comments - Kazuo Takiguchi
Resubmission - Version 2
24 Apr 2017 Submitted Manuscript version 2
22 May 2017 Reviewed Reviewer Report - Sarah Wijtenburg
26 Jun 2017 Author responded Author comments - Kazuo Takiguchi
Resubmission - Version 3
26 Jun 2017 Submitted Manuscript version 3
Publishing
29 Jun 2017 Editorially accepted
12 Jul 2017 Article published 10.1186/s12888-017-1410-3

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
(2)
Haryugaoka Hospital
(3)
Psychiatry Department, Tokyo Metropolitan Tama Medical Center
(4)
Clinical Research Center, Medical Hospital of Tokyo Medical and Dental University
(5)
Ohmiya Kousei Hospital
(6)
Department of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School
(7)
Department of Psychiatry, National Center Hospital of Neurology and Psychiatry
(8)
Department of Hospital Pharmacy, Tokyo Medical and Dental University

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