Table 2 The maintenance treatment medicines
Total sample (n = 60) | Inadequate dose (n = 39) | Adequate dose (n = 21) | p | |
|---|---|---|---|---|
Methadone / Buprenorphine – naloxone sublingual tablet | 52 (86.7%) / 8 (13.3%) | 38 (63.3%) /1 (1.7%) | 14 (23.3%) /7 (11.7%) | 0.002 |
Dose of methadone (mg) | 64.81 ± 13.6 (20–90) | 65.0 ± 11.4 (20–90) | 64.3 ± 18.6 (24–90) | NS |
Blood concentration of methadone (mg/L) (n = 45)a | 0.20 ± 0.1 (0.09–0.47) | 0.19 ± 0.07 (0.09–0.36) N = 35 | 0.24 ± 0.10 (0.12–0.47), N = 10 | NS |
Dose of buprenorphine (mg) | 14.8 ± 5.01 (6–20) | 16.0 | 14.6 ± 5.4 (6–20) | NS |