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Table 5 Polydrug abuse of the patients with low doses of the maintenance treatment medicine

From: Polydrug abuse among opioid maintenance treatment patients is related to inadequate dose of maintenance treatment medicine

Medicine Dose (mg) Adequacy of the dose of the medicine Blood concentration (mg/L) Abused substances based on LC-TOFMS methoda
Methadone 20 Too low dose < 0.10 Alprazolam
Methadone 24 Adequate Not available No substances
Methadone 30 Adequate 0.17 No substances
Methadone 50 Too low dose < 0.10 Oxazepam, temazepam, amphetamine, bupropion
Buprenorphine 6 Adequate Not available No substances
Buprenorphine 8 Adequate Not available No substances
  1. aLiquid chromatography coupled to high-resolution time-of-flight mass spectrometry (LC-TOFMS)