Polydrug abuse among opioid maintenance treatment patients is related to inadequate dose of maintenance treatment medicine

Table 5 Polydrug abuse of the patients with low doses of the maintenance treatment medicine

Medicine	Dose (mg)	Adequacy of the dose of the medicine	Blood concentration (mg/L)	Abused substances based on LC-TOFMS method^a
Methadone	20	Too low dose	< 0.10	Alprazolam
Methadone	24	Adequate	Not available	No substances
Methadone	30	Adequate	0.17	No substances
Methadone	50	Too low dose	< 0.10	Oxazepam, temazepam, amphetamine, bupropion
Buprenorphine	6	Adequate	Not available	No substances
Buprenorphine	8	Adequate	Not available	No substances

^aLiquid chromatography coupled to high-resolution time-of-flight mass spectrometry (LC-TOFMS)

ISSN: 1471-244X