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Table 3 Pre-post comparisons of HAMD-17a and SF-36b for patients completing the 6-week treatment (n = 106)

From: Factors related to the improvement in quality of life for depressed inpatients treated with fluoxetine

Measure

Taiwanese norms

(Mean ± SD)

Week 0

(Mean ± SD)

Week 6

(Mean ± SD)

Difference

(Mean ± SD)

p

Effect size

HAMD-17

 

31.4 ± 6.4

13.7 ± 8.3

−17.7 ± 8.5

<0.001*

−2.093

SF-36

      

 Physical functioning

92.24 ± 16.16

61.5 ± 25.7

63.9 ± 25.4

2.4 ± 23.7

0.299

0.101

 Role physical limitations

83.65 ± 33.27

15.1 ± 30.8

28. 5 ± 41.9

13.4 ± 45.1

0.003*

0.298

 Bodily pain

84.84 ± 19.42

45.3 ± 26.1

50.9 ± 29.2

5.6 ± 24.1

0.018*

0.233

 General Health

69.29 ± 21.27

28.0 ± 22.5

35.9 ± 26.4

7.9 ± 22.8

<0.001*

0.348

 Vitality

68.27 ± 18.66

24.6 ± 19.6

33.7 ± 23.2

9.2 ± 21.9

<0.001*

0.417

 Social functioning

86.81 ± 17.05

33.8 ± 22.9

43.0 ± 26.2

9.2 ± 27.2

<0.001*

0.338

 Role emotional limitations

79.40 ± 36.07

5.7 ± 17.5

23.3 ± 39.1

17.6 ± 40.0

<0.001*

0.441

 Mental health

73.01 ± 16.55

26.7 ± 19.3

37.6 ± 22.2

10.9 ± 23.9

<0.001*

0.457

 Physical component summary

 

39.3 ± 10.0

40.6 ± 10.6

1.3 ± 9.3

0.148

0.142

 Mental component summary

 

23.3 ± 8.62

29.7 ± 11.3

6.4 ± 11.6

<0.001*

0.548

  1. aHAMD-17 = 17-item Hamilton Depression Rating Scale
  2. bSF-36 = Medical Outcomes Study Short-Form-36
  3. *Statistically significant